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This is surprising for 2 reasons 1) that there was this significant bleeding from baby aspirin 2) that a miracle drug from 300bc is being found to have downsides. I'm still an aspirin proponent for treating sunburns and minor ailments. And salycilic acid for my face routine. Fish oil's recent science on hormone regulation and inflammation reduction should make it a first stop. Then there is AKG.
"That means if 1,000 elderly women take aspirin daily for a decade, 11 of them will avoid a heart attack; meanwhile, twice that many will suffer a major gastrointestinal bleeding event that would not have occurred if they hadn’t been taking aspirin." "The U.S. task force wants to strongly discourage anyone 60 and older from starting a low-dose aspirin regimen, citing concerns about the age-related heightened risk for…
And while you're right, that GI bleeding on it's own might not be a huge issue, I suspect a gastroenterologist would want to do a colonoscopy if it does happen, something that patients probably wont to avoid if they can.
This is surprising for 2 reasons 1) that there was this significant bleeding from baby aspirin 2) that a miracle drug from 300bc is being found to have downsides. I'm still an aspirin proponent for treating sunburns and minor ailments. And salycilic acid for my face routine. Fish oil's recent science on hormone regulation and inflammation reduction should make it a first stop. Then there is AKG.
What’s your face routine?
is a precursor to and a metabolite of aspirin (acetylsalicylic acid). It is a plant hormone. The name is from Latin salix for willow tree
"That means if 1,000 elderly women take aspirin daily for a decade, 11 of them will avoid a heart attack; meanwhile, twice that many will suffer a major gastrointestinal bleeding event that would not have occurred if they hadn’t been taking aspirin." "The U.S. task force wants to strongly discourage anyone 60 and older from starting a low-dose aspirin regimen, citing concerns about the age-related heightened risk for…
Anecdote time!
My dad was on a bit too many blood thinners—a prescription, and aspirin.
He’d been feeling weak and a little down for a week. On a Friday night…bam, passed out, in the bathroom, and hit his head.
Went to the ER. When…I’ll elide details…using the restroom, he had a huge GI bleed. They had to put 2 units of blood into him in the ICU.
So, yeah, bleeds can be bad. As bad as a heart attack? No, but they really can sneak up on you.
This piece entirely misses the point of the recommendation. The new recommendation is that aspirin should not be used to prevent heart attack in those without a history of heart disease (ie avoid routine aspirin for "primary prevention"). Aspirin for primary prevention has always been a grey area. The reversal came after a large trial in the New England Journal of Medicine looking at this. The trial showed the decrea…
Edit: Here's the document that actually outlines "what changed" from 2016 to the current draft: file:///Users/nkrumm/Downloads/aspirin-use-cvd-prevention-draft-modeling-report.pdf
This piece entirely misses the point of the recommendation. The new recommendation is that aspirin should not be used to prevent heart attack in those without a history of heart disease (ie avoid routine aspirin for "primary prevention"). Aspirin for primary prevention has always been a grey area. The reversal came after a large trial in the New England Journal of Medicine looking at this. The trial showed the decrea…
The recommendation used to be "just take aspirin, you won't have a heart attack" and now it's "wait, this could be bad, let's qualify that".
He uses this as a lead-in to discuss the concepts of NNT and NNH. It makes sense.
This piece entirely misses the point of the recommendation. The new recommendation is that aspirin should not be used to prevent heart attack in those without a history of heart disease (ie avoid routine aspirin for "primary prevention"). Aspirin for primary prevention has always been a grey area. The reversal came after a large trial in the New England Journal of Medicine looking at this. The trial showed the decrea…
So I am planning to stop now. It seems like I'm a poster child for "stop taking daily aspirin."