11–20 of 163 posts
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
As far as the study goes, it was significant at a p 0.05 level so will wait for replication.
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
I keep reading about these “IU”s on HN, what on earth are they? Here in the uk you just buy “Vitamin D” and take one pill per day. No fine-tuning, unless you need specialised therapy perhaps.
My vitamin D level is only optimal when taking an average of 11000 IU / day (D3 + K2). It hasn't improved my sleep quality. As an example, I woke up at 3:30 am this morning and feel like I haven't slept at all.
Anecdotal, but several accounts I heard from people I know (and some I’ve read — even in this HN discussion, but the most n=1 scientific is gwern) indicate you need to take the vitamin D early in the day or it would harm your sleep quality. It also makes sense biologically, given that you need sunlight to generate it yourself.
Again, anecdotal - but detrimental to my sleep if taken after midday. If I can’t take it until 10am, I skip that day
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
I keep reading about these “IU”s on HN, what on earth are they? Here in the uk you just buy “Vitamin D” and take one pill per day. No fine-tuning, unless you need specialised therapy perhaps.
• Vitamin A: 5,000 IU (upper limit of 10,000 IU)
• Vitamin D: 600 IU
• Vitamin E: 22.4 IU
Totally anecdotal, but I went through a period of insomnia a few years age. It would take several hours to get to sleep. I realised that I had recently started taking vitamin D supplements just before bed and figured it might be connected. Changed to take the supplements in the morning and the insomnia went away.
Apparently D3 inhibits production of melatonin. Can't remember where I read this so not a hugely useful comment but I promise I didn't just make it up! Anecodtally, I've also experienced similar issues taking 1000 IU D3 before bed and having trouble sleeping. I moved the dose to the morning and Boom!, good sleep. Edit: Here is the study. https://pubmed.ncbi.nlm.nih.gov/23665342/ - only a single study but still intere…
Earlier quoted context omitted.
I keep reading about these “IU”s on HN, what on earth are they? Here in the uk you just buy “Vitamin D” and take one pill per day. No fine-tuning, unless you need specialised therapy perhaps.
International units. OTC quantities tend to be quite low, e.g 300-400 IUs, which aren't sufficient unless you're also getting daily sunlight not through a window. 1000-2000 IU is better - widely regarded as safe and no cases I've ever read of of hypervitaminosis, but it's above usual OTC doses. 4000+ daily is pushing it and I have read of cases of toxicity above that, but if you're struggling to get serum levels up t…
Then I moved to Norway. One strength is sold in most stores - 400iu per tablet. You might be able to buy stronger in the pharmacy, but I had to have a prescription for a higher strength when I had low levels.
And to be fair, 2 of those store tablets keeps my levels high enough. So while 400 might be inadequate, 800 certainly isn't. Even without enough sunlight: I literally cannot get enough during the winter because the sun simply isn't strong enough when it happens to be up.
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
I keep reading about these “IU”s on HN, what on earth are they? Here in the uk you just buy “Vitamin D” and take one pill per day. No fine-tuning, unless you need specialised therapy perhaps.
You probably never noticed it, or your pills have low-strength dosages (400 IU), which are quite common to find in pharmacies, and personally I don't even bother with those.
50,000 IUs every 15 days for 8 weeks. I wonder if it would have better effects if they were given 3-4k IUs every day
I keep reading about these “IU”s on HN, what on earth are they? Here in the uk you just buy “Vitamin D” and take one pill per day. No fine-tuning, unless you need specialised therapy perhaps.
The NHS provides some guidance on doses here: https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-...
Earlier quoted context omitted.
International units. OTC quantities tend to be quite low, e.g 300-400 IUs, which aren't sufficient unless you're also getting daily sunlight not through a window. 1000-2000 IU is better - widely regarded as safe and no cases I've ever read of of hypervitaminosis, but it's above usual OTC doses. 4000+ daily is pushing it and I have read of cases of toxicity above that, but if you're struggling to get serum levels up t…
Honestly, OTC quantities vary depending on what is legal where you live. It has been 8-9 years since I lived in the US but nevertheless: At the time, you could buy 1000-2000iu strengths. I worked at a large pharmacy chain and stocked vitamins weekly. Then I moved to Norway. One strength is sold in most stores - 400iu per tablet. You might be able to buy stronger in the pharmacy, but I had to have a prescription for a…
I'm confident that 2,000 IU daily is safe, though.