Still need to get around to trying this. My problem with playing online is not so much the method used, as coordinating everyone and preventing them from being interrupted. This is really easy when you are in a room together. Not so much so when apart.
If only there was some sort of online collaborative audio and video enabled thingie. Cool kids use Twitch I gather (it sounds like a minor STD to me). You could get together with Teams, Zoom, Blue Button, whatever and then play. Organise your online events in a similar form to err ... ... reality and you'll have the same problems to deal with 8) Create a place and arrange to meet. Have a chat and then get on with the…
We have a text and voice/video channel that’s restricted to just the DM and the players, we’ve all got webcams and pick a time where we can dedicate the attention to the game. Small groups also help.
Funnily enough we’re going to be using Talespire for our upcoming game, but all mechanics/tracking goes through DnDBeyond.