Live data from Hacker News

Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

academic.oup.com

11–20 of 61 posts

Re: Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

#13
post #6

I saw a post on NIH studies showing possible benefits and people dismissing it because it wasn't a preponderance of evidence. Totally valid to dismiss a selected sample but made me realize there was more of a basis for its usage than, let's say, bleach. That said, I was wrong, removed . I guess it's too much to ask for people to trust the recommended medicine, perhaps we should get more pro-vaccine conspiracy theorie…

This study was in vivo, not in vitro.

Re: Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

#15
post #4

The whole Ivermectin controversy has been so strange given that it's known to be safe. If it's effective great and if not then there's no harm.

If its effective it means there is a treatment available. If there is a treatment available in the beginning stages of ncov19 then the justification for EUA, by law, becomes invalid. And pfizer and pharma companies lose billions and billions of dollars. Hence why it has been so strange...

You seem to have a misunderstanding of the law. The FDA is allowed to issue EUAs even when other treatments exist.

Re: Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

#16
post #9

Trial group of 62 patients and no parasite screening in those patients - yawn. But could be interesting grounds for a more significant and controlled study with patients with comorbidities.

Do we have any data on the base rate of parasite infections in Lagos?

Depends where -just found a paper showing 54% of school children tested by sample (not seeking medical attention) in at least one area of Lagos. Probably lower in adults but it's not a sub-1% number or even close to it. So were the results due to the anti-parasitic action or something else?

Re: Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

#17
post #5

Please only take this medication by prescription from a medical doctor. Even if these results are replicated, there is a huge difference between 12mg/day IV for 5 days under medical supervision and consuming a tube of apple flavored paste containing 6 grams of ivermectin. Ivermectin is neurotoxic at high doses and can absolutely kill you.

> only take this medication by prescription from a medical doctor.

And, if they prescribe it for treating COVID, look for a better doctor.

Re: Ivermectin shows clinical benefits in mild to moderate COVID19: RCT double-blind

#19
post #15

Earlier quoted context omitted.

If its effective it means there is a treatment available. If there is a treatment available in the beginning stages of ncov19 then the justification for EUA, by law, becomes invalid. And pfizer and pharma companies lose billions and billions of dollars. Hence why it has been so strange...

You seem to have a misunderstanding of the law. The FDA is allowed to issue EUAs even when other treatments exist.

It is you who is mistaken.

Under an EUA, FDA may allow the use of unapproved medical products, or unapproved uses of approved medical products in an emergency to diagnose, treat, or prevent serious or life-threatening diseases or conditions when certain statutory criteria have been met, including that there are no adequate, approved, and available alternatives.

Post reply on HN