Live data from Hacker News

Lies, Damned Lies, and Vaccine Statistics

drrollergator.substack.com

11–20 of 63 posts

Re: Lies, Damned Lies, and Vaccine Statistics

#11
I took the bait, I'm ashamed. I try to keep an open mind, so I read some of it.

The thrust of the article is that vaccines work well at preventing infection, but that if you do get infected, it is _possible_ that you might die at a higher rate. _Possible_ comes from a big spread in the standard deviation of P(death|infected & vaccinated). I didn't check his calculations, I took his numbers at face value and just looked at the charts.

The author uses big standard errors to make claims about what could or could not be true, because the standard errors straddle both favorable and unfavorable statistics for the vaccine.

However when the standard errors are too small for this dubious reasoning, they come out in favor of the vaccine.

The author appears to me to be using motivating reasoning to push an agenda.

Edit: sorry I am not completely right, because I wrote this comment before thoroughly reading the whole article. Sometimes his standard errors come out against the vaccine, and for all I know his math could be right. But I don't want to check the math because I have limited time and I don't care if my death rate goes up given conditions {x, y, z.}

I care if getting the vaccine makes me less likely to get sick and die, which it does, because if you look at all the tables and charts that's exactly what it shows.

Re: Lies, Damned Lies, and Vaccine Statistics

#12
I do think it's very important to be clear what your statistics are saying, and everyone has done a pretty poor job of being clear about that.

But in this case, what people really want and need to know is how well the vaccine is going to prevent them from dying.

They don't care about the difference between "Prevent dying from covid" and "prevent dying from covid once you have covid". The latter simply doesn't matter to them until they have covid, and then it's too late for the vaccine. That statistic is meaningless to the general public.

People only want to know if the vaccine can help them not die. And it absolutely can because it helps prevent getting infected in the first place.

Edit: I just realized the statistic that people want: "How likely are you to die from Covid if exposed to it, vaxed vs unvaxed." Not if you get it. Just if you're exposed to it. And since we don't run tries where we deliberately expose people to viruses, it's going to be a hard number to get.

Re: Lies, Damned Lies, and Vaccine Statistics

#13
> The real world data has shown that the death rate among the vaccinated, if infected with COVID, can be 3 to 5.7 times higher1 than the death rate of the unvaccinated.

Okay… but how much less likely are you to get “infected”?

How are you even defining “infected”, here? If virus gets in your body and then your immune system kills it before it does much damage, were you “infected”? If the answer is no, you've got pretty serious selection bias, because you're completely ignoring everyone who was completely protected by the vaccine in the “vaccinated” group, but paying attention to everyone who didn't really need a vaccine in the “unvaccinated” group: basically ignoring all the really-healthy, great-immune-systems, unlikely-to-die people in the “vaccinated” group so, proportionally, the sicker people take up more room. So you can't even say that the vaccine makes things worse for them! If it improves their chances by 100 times, as Dr. Tom said, but the selection bias is only paying attention to the 0.2% least immune people (those who got infected when exposed after vaccination), you'd expect to see a 5× higher death rate even though the actual death rate is 0.99× lower. (Made-up numbers.)

Re: Lies, Damned Lies, and Vaccine Statistics

#14
post #7
post #6

My theory - pandemic is mostly a religious event. Mind that much of world religions is mostly anti-epidemic advice presented as God's commands (with some world creation myth and some moral advice on top). So people are prone to react with religious fervor in response to each epidemics. And since the main purpose of religion is dividing people on Us vs Them (Us - clean and moral, Them - stained and evil) this is exact…

I think this is only a religious debate in the US where Trump tied it directly to a certain identity people desperately want to maintain or distance themselves from.

I've never heard it referred to as a religious debate in the US. When I hear about anti-vaxxers complaining, it's from a perceived freedom (not religion) standpoint. Maybe there are exceptions for some religious minorities, but I have yet to hear them.

Re: Lies, Damned Lies, and Vaccine Statistics

#15
This article fails to mention the BY FAR most significant benefit of the vaccine which is: achieving herd immunity

We should be as accurate as possible with when talking about vaccine but throwing around statics(or should we say "Vaccine Statistics") like:

> "the death rate among the vaccinated, if infected with COVID, can be 3 to 5.7 times higher than the death rate of the unvaccinated."

is not exactly providing the big picture context needed for a productive social discussion.

The article suggests focusing "real efficacy". Before the vaccine program started there were ~4000 deaths per day in the US, now there are ~100. Clearly it is very effective at reducing death.

Re: Lies, Damned Lies, and Vaccine Statistics

#16
post #11

I took the bait, I'm ashamed. I try to keep an open mind, so I read some of it. The thrust of the article is that vaccines work well at preventing infection, but that if you do get infected, it is _possible_ that you might die at a higher rate. _Possible_ comes from a big spread in the standard deviation of P(death|infected & vaccinated). I didn't check his calculations, I took his numbers at face value and just look…

>The author appears to me to be using motivating reasoning to push an agenda.

Just like the pro-vaccination arguments.

Re: Lies, Damned Lies, and Vaccine Statistics

#17
post #9

This post was flagged. I just vouched for it. I read the whole thing. As far as I can tell, it is accurate. There is not a single comment pointing out any error or misinformation or lie or damned lie. Unless somebody can show that the data and/or interpretation are wrong, it should not be flagged.

Agreed. I also read it carefully, and could not seen any inaccuracies.

Thanks for vouching for it.

Re: Lies, Damned Lies, and Vaccine Statistics

#18
post #9

This post was flagged. I just vouched for it. I read the whole thing. As far as I can tell, it is accurate. There is not a single comment pointing out any error or misinformation or lie or damned lie. Unless somebody can show that the data and/or interpretation are wrong, it should not be flagged.

The post has been up for an hour. The people who will write those comments pointing out errors are probably taking their time to read it and write those comments.

Re: Lies, Damned Lies, and Vaccine Statistics

#19
This is a great post and you can immediately see where they are going with this as soon as he quotes Dr. Tom Frieden.

It makes tons of sense that those who are vaccinated and get infected are more likely to die, simply because it would indicate a failure to develop antibodies and mount an effective immune response to the virus.

That being said I’m not sure such a rant is justified over a tweet like this. Dr. Frieden is more or less correct if you slightly re-word his sentence to: “Getting vaccinated decreases the chance of dying by approximately 100x”.

What I take home from this is that everyone is human, can make simple mistakes, and that we take things written on Twitter far too seriously. I’m sure that Dr. Frieden would not have made such a mistake if he wrote an article that was published somewhere reputable instead of a tweet that could have been sent while waiting for his coffee at Starbucks, or using the toilet.

There is a trade off in communicating science to the public in that using social media, TV, and newspapers reaches more people but almost always distorts the message. I’m not sure how exactly to balance this trade off, but I also think that some amount of responsibility lies with the reader to seek the truth instead of demanding that every sentence they read on the internet be as accurate as a peer reviewed journal.

Re: Lies, Damned Lies, and Vaccine Statistics

#20
The post is conflating vaccine efficacy and effectiveness which are two different epidemiological measures.

It also fails to consider the false positive and false negative rates inherent in these studies. In particular, lots of asymptomatic cases in the vaccinated arm are not caught by efficacy studies (false negatives). So claiming that low death rates are solely a result of reduced infection(as opposed to fighting off infections better) is also a conclusion made hastily.

Death rates and symptomatic cases are much measured much more accurately, and claiming that effectiveness studies have little point once there's vaccine efficacy is available underestimates the challenges of epidemiology.

But the overall point that statistics are hard to understand, easily misused in online arguments is a valid point.

Post reply on HN