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Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

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Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#11
post #7

A January 2021 study in the annals of internal medicine estimating the death rates of non institutionalized patients of .26 percent with age breakdowns . https://www.acpjournals.org/doi/10.7326/M20-5352?utm_source=...

That seems pretty low compared to what is happening here in Belgium.

We are at 22k deaths with +/- 25% of a 11M of the population having been infected (based on serology and statistical estimates).

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#13
post #7

A January 2021 study in the annals of internal medicine estimating the death rates of non institutionalized patients of .26 percent with age breakdowns . https://www.acpjournals.org/doi/10.7326/M20-5352?utm_source=...

For every person that dies (an agonizing death akin to medieval torture), a few more are in intensive care fighting for their lives. For every one of those, others end up in the hospital, spread the disease to others, suffer from “long covid”, or merely suffer greatly. Every person that gets covid adds to the likelihood the disease will become uncontrollable in the long term and endemic.

Keep wearing your masks and social distancing people. It’s hard, it’s a sacrifice, but together we can conquer this disease and return to life “as normal”.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#15
post #14

This is good news. Now maybe Fauci should rethink his idea that people need to wear their masks for another year even after getting vaccinated. One of his reasons was because of worry about the variants.

Wearing masks have benefits beyond covid. Think about how many lives per year we could save from the flu let alone other airborne respiratory viruses if mask wearing was normalized.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#16
This is not well aligned with other research[1] showing the Pfizer and Moderna vaccines perform little better against the B1351 (South Africa) variant than they do against plain old SARS and distantly related bat COVIDs. They're also only semi-effective against the Brazilian P1 variant.

Right now, all of the vaccines are reasonably effective against the variants commonly circulating in the US (including B117), which is what the JAMA article tested. But I worry for how well they'll perform in a few months when the other variants get a foothold.

[1]: https://www.cell.com/cell/pdf/S0092-8674(21)00298-1.pdf

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#17

The immune system still works as advertised.

What’s the purpose of comments like this?

EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election.

The problem was Trump was a completely ineffective and incompetent leader, who didn’t care at all about the things he claimed to care about. Mandatory quarantines and tests for people traveling to America would’ve been a lot of work and Trump was allergic to that. He was a man who preferred the cheers at his rallies over the difficult work of administrating and governing.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#18
The title of this article, which performs an in vitro test, is "Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination". The editorialization in the current Hacker News headline ("Vaccines Are Effective Against Covid Variants") is not warranted.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#19
post #14

This is good news. Now maybe Fauci should rethink his idea that people need to wear their masks for another year even after getting vaccinated. One of his reasons was because of worry about the variants.

Wearing masks have benefits beyond covid. Think about how many lives per year we could save from the flu let alone other airborne respiratory viruses if mask wearing was normalized.

Wearing foam rubber padding all the time has benefits, but that doesn't mean everyone should do it. There are other considerations beyond mere safety.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#20
post #7

A January 2021 study in the annals of internal medicine estimating the death rates of non institutionalized patients of .26 percent with age breakdowns . https://www.acpjournals.org/doi/10.7326/M20-5352?utm_source=...

That seems pretty low compared to what is happening here in Belgium. We are at 22k deaths with +/- 25% of a 11M of the population having been infected (based on serology and statistical estimates).

If I'm not mistaken, the rate in the paper is bigger, 0.25% against 22k/11M = 0.20% in Belgium.

But if the newspaper I read are right, there is a catch: when tests were not available, Belgium counted as a covid death every case where it could be suspected. Even nowadays, in case of comorbidity, covid is always written down as the cause of death. So 22k is probably a maximum, and, taking into accound the 25% uncertainty on the denominator, the real rate could very different.

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