Zolpidem, I use this pill to sleep and works fantastic for me. My MD told me that regular use could lead to dementia and the risk for addiction is considerable. I've tried antidepressants to sleep but always wake up with a headache, the feeling of it it's not great either. But with this one, never had an issue.
Severe brain injury and paralysis temporarily reversed with a sleeping pill
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Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#12Things like these makes me realize how little we know about the functioning of brain. Manipulating brain digitally would be perhaps one of the biggest technological revolution after industrial revolution.
That’s basically singularity
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#13Reading the HN title, I was immediately reminded of the Oliver Sacks book Awakenings[1]. He discovered that the drug L-DOPA could temporarily awaken encephalitis patients from a coma-like state. I wonder if the article's title "Awakening after a sleeping pill" is a reference to that book.
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#14What happens when the sleeping pill wears off? Does the patient revert to his previous state until administered another dose, or does a single dose permanently change the patient?
Essentially they come back to life for a bit and then slither back to their vegetative state.
You could phrase this much more kindly.
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#15Things like these makes me realize how little we know about the functioning of brain. Manipulating brain digitally would be perhaps one of the biggest technological revolution after industrial revolution.
I saw a paper describing a clinical trial of a device which electrically stimulates the median nerve to reduce the severity of tourette's symptoms.
This would be game changing to the Tourette's community. It is so much more than just a speech or tic disorder, and to give the worst affected sufferers their lives back (by reducing the impact of disinhibition, etc) is a fucking miracle.
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#16Hopefully this doesn’t work
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#17Earlier quoted context omitted.
Essentially they come back to life for a bit and then slither back to their vegetative state.
You could phrase this much more kindly.
I believe it would be on you to interpret it more charitably. I'm unsure how you've found a way to take offense with words that aren't readily associated with malice.
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#18https://www.youtube.com/watch?v=4kWKvDj3jD4
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#19Zolpidem, I use this pill to sleep and works fantastic for me. My MD told me that regular use could lead to dementia and the risk for addiction is considerable. I've tried antidepressants to sleep but always wake up with a headache, the feeling of it it's not great either. But with this one, never had an issue.
Dementia as a side effect? Aren’t you scared of that?
Re: Severe brain injury and paralysis temporarily reversed with a sleeping pill
#20Excerpt:
A man, 29-year old, with a history of alcohol abuse suffered from hypoxic-ischemic brain injury after choking on a piece of meat. After an initial, though slow neurological recovery, spontaneous movement and speech disappeared. The patient developed such a severe impairment of arousal that he required intensive auditory and tactile stimulation to maintain a wakeful state. No structural lesions were found using a computerized tomography (CT) scan to explain this secondary deterioration, and conventional EEG-recordings showed no evidence of epilepsy. After a stay in the ICU and neurology department, the patient was transferred to a nursing home without a formal diagnosis explaining his hyporesponsive state. A structural MRI at follow-up showed signs of diffuse atrophy without hydrocephalus.
Eight years passed without any further improvement and neurological follow-up. Eventually, a new nursing home physician with experience in hyporesponsive disorders took over the patient's treatment and performed a new neurological examination to find directions to improve his care. Upon clinical assessment, the now 37-year old patient seemed awake, but showed a complete lack of voluntary movement (akinesia) and absence of speech (mutism). More specifically, the patient showed no affective reactions, initiation of eating or drinking, and remained incontinent. Although the patient showed no signs of spontaneous speech or vocalization on request, he was able to respond to questions or commands with movements with a significant delay (usually a couple of seconds) and with evident ataxia and muscle rigidity. Despite his intact awareness, the patient's initiative was so severely impaired that he remained wheelchair-bound and entirely dependent on nursing care for all daily activities, including the need for enteral tube feeding.
It's incredible how little we still know about some things. They couldn't pin down a cause and this is apparently a significant detail as to why this patient was basically warehoused in a nursing home with no real treatment for literally years until they tried this new thing, which had some short-lived effects.