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An LSD Trip “Off-Switch” May Be Coming Soon

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Re: An LSD Trip “Off-Switch” May Be Coming Soon

#11
post #6

Earlier quoted context omitted.

Do benzodiazepines actually switch it off, or just allow the participant to relax (and maybe sleep it off)?

In my experience they turn the trip off. You can still be awake, but you won’t be tripping any more, the sleep only comes if you actually lay down and try to go to sleep or take a large enough dose of benzos.

Same. I've never had to use it to abort a trip personally, but I've seen it done and the person said it turned it off too.

Re: An LSD Trip “Off-Switch” May Be Coming Soon

#12
So no info on what it actually is. Just some company filing a patent. And the fact that they call it "a neutralizer technology" suggests that it's probably just a bunch of BS combined with previously known drugs to make it patentable.

I'm pretty sure there's at least some published research on using at least one antipsychotic for that and mountains of "folk research" on using benzodiazepines.

Re: An LSD Trip “Off-Switch” May Be Coming Soon

#15
post #2

We already have one. Give someone having a bad trip a Xanax and they're good.

Interesting, I didn't know that. Now I wish I'd had a Xanax after my one trip which kept me awake until 4-5 am after taking acid around noon (otherwise it was an incredible day, it was just annoying not being able to sleep).

Don't benzos have some pretty nasty side effects and/or dependency potential though? Maybe this drug is a bit more targeted / less risky?

Re: An LSD Trip “Off-Switch” May Be Coming Soon

#17
post #2

We already have one. Give someone having a bad trip a Xanax and they're good.

Interesting, I didn't know that. Now I wish I'd had a Xanax after my one trip which kept me awake until 4-5 am after taking acid around noon (otherwise it was an incredible day, it was just annoying not being able to sleep). Don't benzos have some pretty nasty side effects and/or dependency potential though? Maybe this drug is a bit more targeted / less risky?

Dependency issues, some memory loss, coordination. Real concerns if you're going to take it every day or drive or something. Nothing that would present a serious issue for this kind of occasional use.

Re: An LSD Trip “Off-Switch” May Be Coming Soon

#19
post #2

We already have one. Give someone having a bad trip a Xanax and they're good.

Interesting, I didn't know that. Now I wish I'd had a Xanax after my one trip which kept me awake until 4-5 am after taking acid around noon (otherwise it was an incredible day, it was just annoying not being able to sleep). Don't benzos have some pretty nasty side effects and/or dependency potential though? Maybe this drug is a bit more targeted / less risky?

Xanax is a short-acting benzodiazepine

Re: An LSD Trip “Off-Switch” May Be Coming Soon

#20
note: i’m not a doctor or anything related.

Wikipedia says “5-HT2A antagonists block the psychedelic activity of LSD”[0], so wouldn’t 5-ht2a antagonists like mirtazapine work well enough here?

No idea as to how quickly the trip would be tempered, though

[0]: https://en.m.wikipedia.org/wiki/Lysergic_acid_diethylamide

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