Can anyone explain what a "genetically transmitted neurodegenerative prion disease" is? I thought prions were misfolded proteins found in the wild that had to be ingested in order to cause disease. How can they be genetically transmitted?
Definitely not an expert, but I think it means you have a gene which causes eventual production of a prion. I.e., you produce proteins which have the potential to misfold; eventually this happens and prion disease begins.