Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment • Hacker News Board

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#11

Post by DanBC » Thu, Mar 19, 2020, 9:38 PM UTC

Etheryte wrote: post #8

rimliu wrote: post #7

Earlier quoted context omitted.

Most likely none, given the concentration.

I can't find the thread right now, but someone did a back of the napkin calculation that you'd need to have 200 gin tonics a day to reach any kind of a reasonable level.

Is this the thread? https://news.ycombinator.com/item?id=22602008

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#12

Post by celticninja » Thu, Mar 19, 2020, 9:42 PM UTC

Etheryte wrote: post #8

rimliu wrote: post #7

Earlier quoted context omitted.

Most likely none, given the concentration.

I can't find the thread right now, but someone did a back of the napkin calculation that you'd need to have 200 gin tonics a day to reach any kind of a reasonable level.

so persistence is key. got it.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#13

Post by baron_harkonnen » Thu, Mar 19, 2020, 9:42 PM UTC

Etheryte wrote: post #8

rimliu wrote: post #7

Earlier quoted context omitted.

Most likely none, given the concentration.

I can't find the thread right now, but someone did a back of the napkin calculation that you'd need to have 200 gin tonics a day to reach any kind of a reasonable level.

Oh I hope someone can make some original strength tonic water and then g&ts can be of medical value once again!

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#14

Post by capableweb » Thu, Mar 19, 2020, 9:46 PM UTC

Alex3917 wrote: post #9

bulldog13 wrote: post #3

Earlier quoted context omitted.

Are you a doctor or medical professional ?

If you want to see a doctor saying the same thing, just do a search on YouTube. I'm not really sure it changes the credibility of the information.

I wouldn't blindly trust it _just because_ a doctor said it, but I would definitely put more trust in a doctor giving medical advice than someone who is not a doctor or similar. Isn't the whole thing with medical advice and doctors that doctors are being trusted and believed in, meaning they have credibility.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#15

Post by robocat » Thu, Mar 19, 2020, 9:49 PM UTC

Xunxi wrote: post #6

What will the effect of drinking quinine tonic be as a preventative measure?

Wikipedia: In the United States, the US Food and Drug Administration (FDA) limits the quinine content in tonic water to 83 ppm[3] (83 mg per liter if calculated by mass), while the daily therapeutic dose of quinine is in the range of 500–1000 mg,[4] and 10 mg/kg every eight hours for effective malaria prevention (2100 mg daily for a 70 kg adult).

How much less than 83mg/litre is unclear. You would do yourself damage with the sugar should you try to drink enough for a dose. Also it is unclear how effective quinine is compared with hydroxychloroquine.

Finally, quinine can have serious side effects, take care.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#16

Post by fab1an » Thu, Mar 19, 2020, 9:50 PM UTC

A word of warning to all who consider stocking up on and self-medicating with Chloroquine: while this is a well-studied medicine, it can have severe side effects, particularly in the eyes (including blindness). That said, let's hope it has some effect as current anecdata suggests.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#17

Post by odiroot » Thu, Mar 19, 2020, 9:50 PM UTC

Etheryte wrote: post #8

rimliu wrote: post #7

Earlier quoted context omitted.

Most likely none, given the concentration.

I can't find the thread right now, but someone did a back of the napkin calculation that you'd need to have 200 gin tonics a day to reach any kind of a reasonable level.

And acquire cirrhosis before the the virus even threatens your lungs.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#18

Post by jessaustin » Thu, Mar 19, 2020, 9:54 PM UTC

turndown wrote: post #5

bulldog13 wrote: post #3

Earlier quoted context omitted.

Are you a doctor or medical professional ?

Considering there is no edit on the original post, the answer has been in it since you asked the question.

How can we tell if HN comments have been edited?

[I have now edited... but please don't say "I see that you added something in brackets"]

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#19

Post by roenxi » Thu, Mar 19, 2020, 9:54 PM UTC

I wonder if there is a point where literally everyone just gets a dose of chloroquine. My understanding is it stops the virus replicating and so is almost a preventative rather than a treatment.

Re: Bayer donates 3M chloroquine phosphate tablets for potential Covid-19 treatment

#20

Post by viggity » Thu, Mar 19, 2020, 9:55 PM UTC

Does anyone know how quickly the production of Chloroquine Phosphate and Hydroxychloroquine can be ramped up (say, to the tune of 500M people * 7g per "course" = 3.5 million kilograms?

I tried finding out how much chloroquine is prescribed world wide per year, but couldn't find it. It may give us a clue into how much is already being used.

I know that it isn't used except for pregnant women as a malaria treatement because the first line antimalarials aren't proven save in pregnancy, but also that the malaria protozoa has some resistence to Chloroquine in many countries (Ecuador, among others)