I'm not sure if it's an exact fit, but dropbox used to have pyston: https://github.com/dropbox/pyston The blog posts by Kevin Modzelewski went into the internals: https://blog.pyston.org/ Also by the same person, a good article on Python's performance: http://blog.kevmod.com/2016/07/why-is-python-slow/ As a side comment: On the subject of type inference, I really come to like python's type hints. I don't use mypy its…
https://github.com/python/mypy/tree/master/mypyc
and this new recent issue that mentions targeting LLVM or other targets