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MSI-1436 stimulates regeneration of heart and multiple other tissues

nature.com

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Re: MSI-1436 stimulates regeneration of heart and multiple other tissues

#11

Post by gingabriska »

missosoup wrote: post #8
rootw0rm wrote: post #5

Earlier quoted context omitted.

labs in India and China.

India has been pretty open and vocal about ignoring pharma patents when it comes to medications. They put the needs of the people above the financial wants of the industry. It's been a cause of tension in trade negotiations.

>India has been pretty open and vocal about ignoring pharma patents when it comes to medications. They put the needs of the people above the financial wants of the industry.

US doesn't put as much pressure because India used "Bhopal Gas Plant Tradegy" for negotiation.

If US really wanted to enforce anything, they could have simply banned outsourcing to India.

There is lots of damage US can do to India on that front, they don't care enough for now for it to matter.

Re: MSI-1436 stimulates regeneration of heart and multiple other tissues

#13

Post by jakeogh »

jokowueu wrote: post #9
rootw0rm wrote: post #3

Earlier quoted context omitted.

patents don't mean shit. if it's safe, effective, and profitable I'll be able to custom order it soon enough.

Dep nding on how complex the molecule is sometimes they won't even be able to make it . More than the half the group buys on that specific longevity forum failed

Failed like nobody committed to the synthesis?

Re: MSI-1436 stimulates regeneration of heart and multiple other tissues

#14

Post by chrisco255 »

bitwize wrote: post #7

...in zebrafish. Settle down, the answer to all your health problems is still fasting.

"It is particularly noteworthy that MSI-1436 stimulates tissue regeneration in both zebrafish and adult mice, two widely divergent species that are separated by approximately 450 million years of evolution."

Also paper explained that the drug had been applied in Phase 1 clinical trials with humans as a treatment for diabetes and obesity.

"Importantly, the doses we have shown to be effective in stimulating tissue regeneration are 5–50-times lower than the maximum well-tolerated human dose."

Re: MSI-1436 stimulates regeneration of heart and multiple other tissues

#15

Post by therein »

rootw0rm wrote: post #10
jokowueu wrote: post #9

Earlier quoted context omitted.

Dep nding on how complex the molecule is sometimes they won't even be able to make it . More than the half the group buys on that specific longevity forum failed

that's absolutely true, i can't deny that. my experience is mostly with cathinones, phenethylamines, and a few substituted amphetamines. oh, and some tryptamines.

I remember getting NSI-189 synthesized by a Polish lab back in the day. An interesting time of my life.

Re: MSI-1436 stimulates regeneration of heart and multiple other tissues

#18

Post by DrAwdeOccarim »

therein wrote: post #15
rootw0rm wrote: post #10

Earlier quoted context omitted.

that's absolutely true, i can't deny that. my experience is mostly with cathinones, phenethylamines, and a few substituted amphetamines. oh, and some tryptamines.

I remember getting NSI-189 synthesized by a Polish lab back in the day. An interesting time of my life.

Fascinating chemical. Looks like you can buy it around a lot of places now-a-days. Did you notice any benefits from a nootropic standpoint?
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