Pivotal CRISPR patent battle won by Broad Institute • Hacker News Board

Re: Pivotal CRISPR patent battle won by Broad Institute

#11

Post by djsumdog » Tue, Sep 11, 2018, 6:32 PM UTC

kowdermeister wrote: post #2

What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?

Australian universities hold the patent on Wi-Fi. A fraction of sales of all hardware Wi-Fi devices goes to fund higher education in Australia.

I find it odd that we have state run/non-profit universities fighting over this. Something about the funding model at the academic level is truly fundamentally broken.

Re: Pivotal CRISPR patent battle won by Broad Institute

#12

Post by djsumdog » Tue, Sep 11, 2018, 6:36 PM UTC

sphix0r wrote: post #5

I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!

Lobste.rs is open source and you could potentially spin up an instance of it specific to some topic you're interested in.

https://write.narwhal.space/ was an attempt at making an instance for writers, but it seems to have gone into disrepair.

Re: Pivotal CRISPR patent battle won by Broad Institute

#13

Post by rotexo » Tue, Sep 11, 2018, 7:05 PM UTC

Maxion wrote: post #4

kowdermeister wrote: post #2

What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?

It's good to keep in mind that CRISPR is but one technique to do gene splicing, it's not the concept itself. Different ways will be discovered now that it's proven to be viable.

It is also worth noting that TALENs were implemented for genome editing [0] before CRISPR/Cas9 [1]. And that there are ongoing trials in human subjects that use TALENs for editing instead of Cas9 [2].

Though I agree with a sibling comment that we might not find another system with the same advantages as CRISPR/Cas9 (ie, only having to generate RNAs to engineer site specificity, rather than the more intensive task of generating a protein coding sequence like you do with TALENs).

[0] https://www.ncbi.nlm.nih.gov/pubmed/21179091 [1] https://www.broadinstitute.org/what-broad/areas-focus/projec... [2] http://www.sciencemag.org/news/2018/09/new-gene-editing-trea...

Re: Pivotal CRISPR patent battle won by Broad Institute

#14

Post by technobabble » Tue, Sep 11, 2018, 7:25 PM UTC

sphix0r wrote: post #5

I'm wondering, is there a hacker news for biohacking related stuff? I have the feeling that there is a lot of progress being made in gene therapy technology these days. Having a friend who's life would be enhanced by gene therapy, I'm highly interested!

Sadly, I don't think so. Check your local meetups. Additionally, SynBioBeta has been an ok source for recent biotech news.

Re: Pivotal CRISPR patent battle won by Broad Institute

#15

Post by perl4ever » Thu, Sep 13, 2018, 4:23 AM UTC

hprotagonist wrote: post #3

kowdermeister wrote: post #2

What would a world with commercialized CRISPR technology look like? Will they just sit in the back and collect fees like the MP3 patent owners? Or will they spin-off and became the Google of DNA editing?

we’re about to find out. Editas Pharmaceuticals is, i believe, the sole commercial licensee by the Broad for CRISPR/Cas-9, and they are scheduled to begin human trials for a rare form of blindness in October.

I would be very interested in knowing more about how Arrowhead Pharmaceuticals compares. The buzzword seems to be "RNA interference", but I don't really know what that means in context.