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An Augmented Reality Microscope for Cancer Detection

research.googleblog.com

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Re: An Augmented Reality Microscope for Cancer Detection

#11

Post by killjoywashere »

cstavish wrote: post #4

Those familiar with the field will recognize an augmented reality microscope as an incomplete alternative to, or stepping-stone towards AI applied to whole-slide images, which are multi-resolution images of more or less identical quality quality to that of a microscope. For some use-cases, deploying AI to microscopic fields of view is a viable, lower-cost alternative to creating whole-slide images and running AI on t…

Exhaustive search is definitely a high value option. But let's consider dermpath. Where the entire lesion is probably in the field of view at 4x, but the number of possible classes may be high (bullous lesions, anyone?). In that case, "90% Bowen's disease, 3% inflamed Seborhheic keratosis, and 7% other" is useful, especially if you knew the machine had been trained on everything in Weedon.

Re: An Augmented Reality Microscope for Cancer Detection

#14

Post by jsolson »

cstavish wrote: post #4

Those familiar with the field will recognize an augmented reality microscope as an incomplete alternative to, or stepping-stone towards AI applied to whole-slide images, which are multi-resolution images of more or less identical quality quality to that of a microscope. For some use-cases, deploying AI to microscopic fields of view is a viable, lower-cost alternative to creating whole-slide images and running AI on t…

> (whole-slide scanners are a bit expensive)

Huh... Why? It _seems_ like a problem with an easy (and cheap) solution, given how readily available (and cheap!) suitably precise cartesian bots are these days, combined with high-quality digital microscopes and the state of modern image alignment algorithms.

What am I missing here?

Re: An Augmented Reality Microscope for Cancer Detection

#15

Post by dpeckett »

jsolson wrote: post #14
cstavish wrote: post #4

Those familiar with the field will recognize an augmented reality microscope as an incomplete alternative to, or stepping-stone towards AI applied to whole-slide images, which are multi-resolution images of more or less identical quality quality to that of a microscope. For some use-cases, deploying AI to microscopic fields of view is a viable, lower-cost alternative to creating whole-slide images and running AI on t…

> (whole-slide scanners are a bit expensive) Huh... Why? It _seems_ like a problem with an easy (and cheap) solution, given how readily available (and cheap!) suitably precise cartesian bots are these days, combined with high-quality digital microscopes and the state of modern image alignment algorithms. What am I missing here?

A lot of that cost comes from all the supporting hardware and certified software. Plus a lot of the machines have to be designed for high throughput applications.

Re: An Augmented Reality Microscope for Cancer Detection

#16

Post by leibnizwasright »

cstavish wrote: post #4

Those familiar with the field will recognize an augmented reality microscope as an incomplete alternative to, or stepping-stone towards AI applied to whole-slide images, which are multi-resolution images of more or less identical quality quality to that of a microscope. For some use-cases, deploying AI to microscopic fields of view is a viable, lower-cost alternative to creating whole-slide images and running AI on t…

I agree with you, and there is several companies already doing this for whole slides. In addition, people should also understand that more than 1 slide is necessary for a high quality analysis of the cancer. From the top of my head, I remember Definiens (http://definiens.com) that develops software that does whole slide analysis and HalioDX (http://www.haliodx.com/) that does the same and use it as auxiliary for colon cancer treatment.
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