they used "projection lithography, contact photolithography, and deep reactive ion etching
–DRIE- to fabricate silicon-based TNT devices.
not clear what's proprietary.
Tissue Nanotransfection
11–17 of 17 posts
Re: Tissue Nanotransfection
#12Knowing a little inside info about this development I must add a big word of caution on this science. It may be possible to add this type of coding in an optical format, in short the code may be able to be added say to a video and when someone watches the video the optical tissues in their eyes and retina may begin to transfer into whatever form of tissue is coded. This may indeed be able to effect brain tissue by this route of administration and that is terrifying!
Re: Tissue Nanotransfection
#13Ok, paper supposedly published here but searching finds no articles http://www.nature.com/nnano/index.html
I think it's this one https://www.nature.com/nnano/journal/vaop/ncurrent/full/nnan...
...which has reference #14 has Sen listed as the author of another article (can't find direct link), here's #14 though:
Sen, C. K. & Ghatak, S. miRNA control of tissue repair and regeneration. Am. J. Pathol. 185, 2629–2640 (2015).
Re: Tissue Nanotransfection
#14So I was curious about this and read the supplemental pdf, thank you justintocci. The technology hinges on Nanochannel Electroporation as the storage and delivery vehicle for the DNA. Found the following paper (scrapped the url from Wiley) that goes into detail. The potential here is insane!
Joined Hacker News just to share it. :)
http://onlinelibrary.wiley.com/store/10.1002/advs.201500111/...
Re: Tissue Nanotransfection
#15David Langford had a really great FAQ about this technology over on the comp.basilisk FAQ newsgroup:
Re: Tissue Nanotransfection
#16Knowing a little inside info about this development I must add a big word of caution on this science. It may be possible to add this type of coding in an optical format, in short the code may be able to be added say to a video and when someone watches the video the optical tissues in their eyes and retina may begin to transfer into whatever form of tissue is coded. This may indeed be able to effect brain tissue by th…
Doesn't this require a physical package of some sort of bio material to be delivered to the cell, with electricity being used to open the cell membranes and push it through via ions? If I'm understanding that correctly, then how do you make the leap to optical-only transfer? It's almost as if you're claiming that an optical signal could somehow cause a buffer-overflow exploit in the cone/rod cells of a human eye, and then root the cell's "kernel" and start making run-time patches. And that sounds like a completely different scientific breakthrough than what this TNT stuff sounds like. could you elaborate any further?
Re: Tissue Nanotransfection
#17Knowing a little inside info about this development I must add a big word of caution on this science. It may be possible to add this type of coding in an optical format, in short the code may be able to be added say to a video and when someone watches the video the optical tissues in their eyes and retina may begin to transfer into whatever form of tissue is coded. This may indeed be able to effect brain tissue by th…
Doesn't this require a physical package of some sort of bio material to be delivered to the cell, with electricity being used to open the cell membranes and push it through via ions? If I'm understanding that correctly, then how do you make the leap to optical-only transfer? It's almost as if you're claiming that an optical signal could somehow cause a buffer-overflow exploit in the cone/rod cells of a human eye, and…
Does sound interesting tho, just extrapolating but light/photons do contain energy and hence may just be able to initiate such an action. May depend on the type of display being used .