There are a number of problems with nuclear power.
1. The world's uranium supply won't actually go that far [1].
2. A lot of places aren't suitable for nuclear reactors (eg they're seismically active).
3. We have to trust either corporations or governments to run such plants. Corporations will tend to maximize short term profits at the cost of long term safety. Governments will tend to do the same for budgetary reasons.
4. We'd create a whole bunch of radioactive slag that we honestly have no good way of dealing with.
So far it seems the best power source we have is hydroelectric. Of course it's only possible in some places. This can devastate certain species (eg salmon) but in terms of cost, risks, environmental impact and power output, hydro is hard to beat if it's an option.
Solar has been on a stellar (pardon the pun) rise for some years simply because the cost of cells has decreased by way more than I ever would've predicted.
Widespread electric vehicles are still hindered by the relative expense and scalability issue of batteries, notably how much lithium we have available as well as the environmental impact of mining the necessary materials. It does seem like we're one big battery breakthrough away from completely changing this landscape however.
Wind has a place but I think will remain a niche energy source.
I increasingly have the view the the economic production of electricity from nuclear fusion is a pipe dream. The temperatures are too high, magnetic containment seems too problematic and, worse, the neutron emissions are a big problem (yes, yes, I know about He3).
This does seem like it's a problem we're going to have to solve this century.
[1] https://en.wikipedia.org/wiki/Peak_uranium