Earlier quoted context omitted.
Its fine in a hypervisor. It has excellent Xen support, but you can use others too; it has all the virtio drivers for KVM for example now. What is the issue with your hardware?
I am not at home, but as I recall, the kernel freezes during boot for both the 32 bit and 64 bit versions. The 32 bit version of OpenBSD also freezes during kernel boot but the 64 bit version does not. I know it is not an EFI issue as legacy booting is turned on.
This probably isn't the best forum to give you a hand. Can you hit one of the IRC channels or mailing lists?