I wonder how many mental illnesses are the result of imbalances in foreign organic matter/microbes/fungi/dietary issues and not issues fundamental to the brain itself?
Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
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Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#12Wow sounds like a major breakthrough. How did they not notice this before?
It took thirty years for the medical establishment to accept the hypothesis that the bacteria H. pylori was the cause of peptic ulcer disease, rather than excess stomach acid.
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#13Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#14This seems like potentially an incredibly important breakthrough with a perplexingly weird title. Different brain regions? Different to what? From reading the study, the novelty is not about the "difference" of the brain regions, but the fact that fungal infection is found in AD patients at all. The controls had no infection, not different infections in their brains.
I'm curious if the title makes sense to people in the field or is this weird to them too?
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#15There was recent speculation that alzheimer's was transmissible (prion thing). The transmissibility would make sense if it were actually the fungi causing the build up of the proteins and other damage.
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#16This seems like potentially an incredibly important breakthrough with a perplexingly weird title. Different brain regions? Different to what? From reading the study, the novelty is not about the "difference" of the brain regions, but the fact that fungal infection is found in AD patients at all. The controls had no infection, not different infections in their brains. I'm curious if the title makes sense to people in…
As a layman, i understood the title correctly I guess. That there were fungi not just on one spot, but different (ie several) regions.
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#17I wonder how many mental illnesses are the result of imbalances in foreign organic matter/microbes/fungi/dietary issues and not issues fundamental to the brain itself?
An old but interesting article and discussion related to your question:
http://www.theatlantic.com/magazine/print/1969/12/how-your-c...
https://news.ycombinator.com/item?id=3573694
Articles somehow related to the subject:
http://www.nature.com/news/the-tantalizing-links-between-gut...
http://universityofcalifornia.edu/news/do-gut-bacteria-rule-...
http://www.scientificamerican.com/article/gut-second-brain/
http://www.theverge.com/2013/8/21/4595712/gut-feelings-the-f...
http://newsroom.ucla.edu/portal/ucla/changing-gut-bacteria-t...
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#18Hi, I do research using the same methods: immunohistochemistry. This was done with rabbit polyclonal antibodies. The key being polyclonal. We don't know what those antibodies are really staining. The difference, however, is intriguing.
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#19All of the Alzheimer's patients were 79 or older, while all of the control patients were younger than 79 except for one. More than half of the control patients were under 60. That doesn't seem like a very good control to me.
Re: Different Brain Regions Are Infected with Fungi in Alzheimer’s Disease
#20This seems like potentially an incredibly important breakthrough with a perplexingly weird title. Different brain regions? Different to what? From reading the study, the novelty is not about the "difference" of the brain regions, but the fact that fungal infection is found in AD patients at all. The controls had no infection, not different infections in their brains. I'm curious if the title makes sense to people in…
As a layman, i understood the title correctly I guess. That there were fungi not just on one spot, but different (ie several) regions.
So, interpreting "different" as "multiple"? Seems unnecessary to use an ambiguous word. And then an ambiguous word that is not actually the main point of the study.