Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
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Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#2Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#3Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
What kinds of disorders and diseases will you be testing for?
Will your tests be available direct-to-consumer, or will patients have to go through health provider gatekeeping?
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#4Bioinformatician here. When you say RNA testing, you mean RNA-seq? Gene expression? If yes, then do you think blood samples will be enough to make these type of diagnosis? I imagine you will probably need tissue specific samples to make some of these disease predictions.
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#5Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
Hey Dave, how does RNA sequencing work for an individual customer? Do you plan to have something like the 23andMe collection kit?
In my understanding human cells have may different types of RNA, which one are you sequencing?
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#6Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
What kinds of disorders and diseases will you be testing for? Will your tests be available direct-to-consumer, or will patients have to go through health provider gatekeeping?
or will patients have to go through evil health provider gatekeeping?
FTFY :)
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#7Bioinformatician here. When you say RNA testing, you mean RNA-seq? Gene expression? If yes, then do you think blood samples will be enough to make these type of diagnosis? I imagine you will probably need tissue specific samples to make some of these disease predictions.
Hi,
Great question.
We're developing tests around a recently discovered type of RNA called circular RNA. Tissue-specific circular RNAs are present in blood, and so that's how it's possible to use a blood test instead of having to go to tissue like you would with traditional mRNA-seq.
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#8Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
Hey Dave, how does RNA sequencing work for an individual customer? Do you plan to have something like the 23andMe collection kit? In my understanding human cells have may different types of RNA, which one are you sequencing?
We plan to offer testing through your doctor, rather than direct to consumer.
We are measuring circular RNAs.
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#9Earlier quoted context omitted.
What kinds of disorders and diseases will you be testing for? Will your tests be available direct-to-consumer, or will patients have to go through health provider gatekeeping?
or will patients have to go through evil health provider gatekeeping? FTFY :)
I was trying not to editorialize too much. :-)
Re: Cofactor Genomics (YC S15) Pursues RNA Testing, Offers Better Diagnoses Than DNA
#10Hi everyone! Dave Messina from Cofactor Genomics here. I'd be happy to answer any questions you might have. We're excited to launch!
What kinds of disorders and diseases will you be testing for? Will your tests be available direct-to-consumer, or will patients have to go through health provider gatekeeping?
We are looking at Parkinson's, heart disease, and cancer initially.