Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
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Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#2Has this been found in other tissues?
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#3Has this been found in other tissues?
Iirc yes. Viral persistence and viral reservoirs are the terms to search for
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#4I'd be curious to look for any investigation into whether extended paxlovid treatment fixes a significant subset of long COVID.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#5I'd be curious to look for any investigation into whether extended paxlovid treatment fixes a significant subset of long COVID.
they’ve done 15 days all null and the 25 day one was null but has some unique labs they tested but haven’t posted yet.
Paxlovid does something to antiviral genes and shows there’s something there though in secondary analysis (not posted but has been presented at conferences)
sadly Paxlovid doesn’t actually get rid of the viral pieces remaining and a PROTAC or other therapy might be necessary to degrade the proteins.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#6Has this been found in other tissues?
strongest evidence so far in gut and immune cells for living organisms.
They did find it in the brain of one patient when doing an unrelated procedure at the NIH. That could be due to many things though. General findings around the CSF/brain have been negative.
Autopsy - https://www.nature.com/articles/s41586-022-05542-y
Long covid - https://www.thelancet.com/journals/laninf/article/PIIS1473-3...
Also this exists in both children and adults.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#7The science is interesting but I must admit I learned a new word today.
A deceased person is also a decedent. Adjective vs noun. Cool.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#8The science is interesting but I must admit I learned a new word today. A deceased person is also a decedent. Adjective vs noun. Cool.
Yes, but deceased is also a noun. The Economist's Style Guide would not approve.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#9After seeing studies like this, and how the shingles vaccine reduces dimensia, I have become increasingly convinced that it’s bad to get almost any disease, even transiently. I used to think that it was kind of good to train your immune system (kind of whatever doesn’t kill you makes you stronger). I no longer believe that. I believe that diseases often cause unknown effects and it’s better to avoid disease entirely, that vaccines are actually more beneficial than current studies show in this regard, and new universal vaccines to prevent the common cold and flu will likely have significant health span improvements over time beyond the acute prevention of symptoms.
Re: Autopsy Study Finds Replicating SARS-CoV-2 in the Hearts of Long Covid
#10After seeing studies like this, and how the shingles vaccine reduces dimensia, I have become increasingly convinced that it’s bad to get almost any disease, even transiently. I used to think that it was kind of good to train your immune system (kind of whatever doesn’t kill you makes you stronger). I no longer believe that. I believe that diseases often cause unknown effects and it’s better to avoid disease entirely,…
having posted on this topic for years, your comment is the first I’ve seen come to this rational conclusion. usually people double down on their original perspective