Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
1–10 of 122 posts
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#2Pro: Salk Institute
Con: Preliminary Research, In Vitro
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#3Pro: Salk Institute Con: Preliminary Research, In Vitro
Salk? You mean the vaccine guy? /s
And also, apparently, the registered trademark?
> The researchers found that high levels of amyloid beta were associated with cellular inflammation and higher rates of neuron death. They demonstrated that exposing the cells to THC reduced amyloid beta protein levels and eliminated the inflammatory response from the nerve cells caused by the protein, thereby allowing the nerve cells to survive.
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#4Pro: Salk Institute Con: Preliminary Research, In Vitro
Con: from 2016 w. no followup?
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#5This appears to be dated 2016. Did the preliminary results amount to anything?
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#6This appears to be dated 2016. Did the preliminary results amount to anything?
Human trial in 2025 looks promising?
https://pubmed.ncbi.nlm.nih.gov/41160460/#:~:text=ResultsAt%...
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#7Man, too bad weed gives me bad panic attacks. Alzheimers is the scariest disease I know so maybe if the studies pan out in time and it becomes a standard preventative, I might consider trying again.
But somehow I doubt it will be found to be that effective.
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#8Remove them and replace them with...Doritos?
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#9There are easily hundreds of compounds that can reduce beta-amyloid in vitro. This is a decade-old nothingburger.
Re: Cannabinoids remove plaque-forming Alzheimer's proteins from brain cells (2016)
#10I only had time to skim the paper. Notably, the effect is concentration dependent and required high concentrations of THC. The chart shows it really starting in the 0.1uM range and then taking off in the 1uM range.
I don’t know what levels are achieved during normal use but I did find some studies that successfully killed a lot of hippocampal neuronal cells after 6 days at 1uM range. So the levels of THC observed in this study appear to be in the same range where things start getting really disrupted in cells.
In other words, don’t expect to replicate these results with normal recreational use.