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Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

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1–10 of 163 posts

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#2
This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too.

Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#4
post #3

> and results published Wednesday show it worked nearly as well in men. So not as well? Is there a biological reason for this? Also, is it typical to do such studies on single genders rather than on a mix of humans?

Receptive PIV sex has 2% transmission rate, PIA is 20%. Cis men don't have a vagina, so...

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#5
post #4
post #3

> and results published Wednesday show it worked nearly as well in men. So not as well? Is there a biological reason for this? Also, is it typical to do such studies on single genders rather than on a mix of humans?

Receptive PIV sex has 2% transmission rate, PIA is 20%. Cis men don't have a vagina, so...

There's also a chance that the countries they were able to / encouraged to test in are quite hostile to LGBTQ+ people

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#6
post #4

Earlier quoted context omitted.

Receptive PIV sex has 2% transmission rate, PIA is 20%. Cis men don't have a vagina, so...

There's also a chance that the countries they were able to / encouraged to test in are quite hostile to LGBTQ+ people

This is mentioned in the article.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#8

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

There's a shot that lasts a couple months mentioned in the article.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#9

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

There is a generic daily pill (Truvada), a more expensive one (Descovy) and an every two months shot (Apretude.)

Apretude has lower efficacy than Descovy or Truvada, but once you factor in human error in taking a daily pill regimen, it is more even. Human error is a significant factor since the current treatment protocols say if you’re not sure whether or not to take it, it is safer to skip than to accidentally double the dose.

Re: Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

#10
post #4
post #3

> and results published Wednesday show it worked nearly as well in men. So not as well? Is there a biological reason for this? Also, is it typical to do such studies on single genders rather than on a mix of humans?

Receptive PIV sex has 2% transmission rate, PIA is 20%. Cis men don't have a vagina, so...

To further elaborate, the anal mucous membrane is thinner than that of the vagina, so it’s easier for HIV to transmit that way.
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