Weight-loss drug found to shrink muscle in mice, human cells
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Re: Weight-loss drug found to shrink muscle in mice, human cells
#2I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#3I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#4It seems the article isn't just saying it's heart muscle that's being lost but regular muscle in general. Even more so than in a low calorie diet.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#5As a coder, I'm realising more and more that the human body isn't so different from a computer. When you try to fix something without having complete understanding of all the relevant parts of the system, you will invariably introduce new issues. With a machine as complex as the human body, it seems inevitable that the field of medicine would be a game of whac-a-mole. Finding solutions which don't create new problems is hard and should not be taken for granted.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#6It seems the article isn't just saying it's heart muscle that's being lost but regular muscle in general. Even more so than in a low calorie diet.
There's a linked article saying that 40% of the weight loss is muscle.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#7I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
The first link goes to the study and it does mention the ingredient: https://www.sciencedirect.com/science/article/pii/S2452302X2...
Re: Weight-loss drug found to shrink muscle in mice, human cells
#8well that's a weight reduction too!
on a more serious note, could it be that the load on the muscle gets lower so they adjust?
8% reduction for 30% body weight reduction sounds reasonable to me at first glance
Re: Weight-loss drug found to shrink muscle in mice, human cells
#9I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
The first link goes to the study and it does mention the ingredient: https://www.sciencedirect.com/science/article/pii/S2452302X2...
I am talking about UAlberta's title specifically.
Re: Weight-loss drug found to shrink muscle in mice, human cells
#10It seems the article isn't just saying it's heart muscle that's being lost but regular muscle in general. Even more so than in a low calorie diet.
There's a linked article saying that 40% of the weight loss is muscle.
Outside of cardiac muscle, which is a bit worrisome, 40% of weight loss being from muscles is incredibly typical for any diet that sheds pounds.
There are very complex dietary regimes that can be followed to minimize this, but most studies have shown that they don't save any time compared to losing weight and then working to get the muscle back afterwards.
> Dyck’s study comes on the heels of a commentary published in the November issue of The Lancet by an international team of researchers from the U of A, McMaster and Louisiana State University who examined emerging research showing that up to 40 per cent of the weight lost by people using weight-loss drugs is actually muscle.
This is, again 100% typical of what happens with caloric restriction.