AstraZeneca unveils successes in treatment of lung cancer
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Re: AstraZeneca unveils successes in treatment of lung cancer
#2Re: AstraZeneca unveils successes in treatment of lung cancer
#3It is about Osimertinib, sold under the brand name Tagrisso.
It works (in “statistically significant and highly clinically meaningful” manner) against certain types of lung cancer when administered on early stage.
It was provisionally approved after success in phase 1 trial by FDA in 2015 and by EMA in 2016.
Side effects:
Very common (greater than 10% of clinical trial subjects) adverse effects include diarrhea, stomatitis, rashes, dry or itchy skin, infections where finger or toenails abut skin, low platelet counts, low leukocyte counts, and low neutrophil counts.
Common (between 1% and 10% of clinical trial subjects) adverse effects include interstitial lung disease.
Re: AstraZeneca unveils successes in treatment of lung cancer
#4It is about Osimertinib, sold under the brand name Tagrisso. It works (in “statistically significant and highly clinically meaningful” manner) against certain types of lung cancer when administered on early stage. It was provisionally approved after success in phase 1 trial by FDA in 2015 and by EMA in 2016. Side effects: Very common (greater than 10% of clinical trial subjects) adverse effects include diarrhea, stom…
That doesn't sound too bad if it can cause lung cancer to regress.
Re: AstraZeneca unveils successes in treatment of lung cancer
#5It is about Osimertinib, sold under the brand name Tagrisso. It works (in “statistically significant and highly clinically meaningful” manner) against certain types of lung cancer when administered on early stage. It was provisionally approved after success in phase 1 trial by FDA in 2015 and by EMA in 2016. Side effects: Very common (greater than 10% of clinical trial subjects) adverse effects include diarrhea, stom…
Side effects do not realy sound bad so, as someone who went through a light, comparatively, chemo I saw a lot worse with other patients. Plus, the alternative is lung cancer in late stages. And you sure as hell don't want that!
It is really good to see progress in cancer treatment so!
Re: AstraZeneca unveils successes in treatment of lung cancer
#6Hey onco-nosology nerds: Is there a cell-typed unambiguous classification system, research, and clinical treatment protocol nexus attempting to capture and disseminate information on all cancer types in a more precise and organized effort?
Re: AstraZeneca unveils successes in treatment of lung cancer
#7Didn’t Cuba have a vaccine for lung cancer? I seem to recall seeing one in a documentary (maybe a Michael Moore film?)
Re: AstraZeneca unveils successes in treatment of lung cancer
#8Didn’t Cuba have a vaccine for lung cancer? I seem to recall seeing one in a documentary (maybe a Michael Moore film?)
My father died of lung cancer. I also ran a failed medical tourism company which sent people to get this treatment in Cuba. More modern versions of the Cuban treatment are now few approved in the USA as immunotherapy. Didn’t save my dad
Re: AstraZeneca unveils successes in treatment of lung cancer
#9Hey onco-nosology nerds: Is there a cell-typed unambiguous classification system, research, and clinical treatment protocol nexus attempting to capture and disseminate information on all cancer types in a more precise and organized effort?
I don't know if this is what you mean, but Foundation Medicine has a biobank of genomic data (HIPAA) with cancer patients' genomic profiles.[1] It's pan-tumor and pan-cancer.
EDIT: if you're looking for more of a "what is the current best known treatment plan for xyz" then this might not be what you're looking for. The standard of care is very much changing very often, I don't know if anyone has a solution for disseminating that. foundation medicine also has a patient-focused side where you can get your own test and get pointed to the treatment for your cancer genomic profile [2]. The societies are probably trying the most to get all of that data available/up-to-date (for example: the American Cancer Society)
[1] https://www.foundationmedicine.com/service/genomic-data-solu...
[2] https://www.foundationmedicine.com/patient/start-with-step-o...
Re: AstraZeneca unveils successes in treatment of lung cancer
#10Didn’t Cuba have a vaccine for lung cancer? I seem to recall seeing one in a documentary (maybe a Michael Moore film?)
My father died of lung cancer. I also ran a failed medical tourism company which sent people to get this treatment in Cuba. More modern versions of the Cuban treatment are now few approved in the USA as immunotherapy. Didn’t save my dad
So sorry to hear about your dad!
> I also ran a failed medical tourism company which sent people to get this treatment in Cuba
Why did the company fail? How effective was the treatment?