Loss of epigenetic information as a cause of mammalian aging
1–10 of 57 posts
Re: Loss of epigenetic information as a cause of mammalian aging
#2Wrong title: "Loss of epigenetic information as a cause of mammalian aging"
Re: Loss of epigenetic information as a cause of mammalian aging
#3What makes me somehow believe in the information theory of aging is that old people look "noisy".
Re: Loss of epigenetic information as a cause of mammalian aging
#4Wrong title: "Loss of epigenetic information as a cause of mammalian aging"
The title here is the fourth item in the list of highlights:
• Cellular responses to double-stranded DNA breaks erode the epigenetic landscape
• This loss of epigenetic information accelerates the hallmarks of aging
• These changes are reversible by epigenetic reprogramming
• By manipulating the epigenome, aging can be driven forward and backward
Re: Loss of epigenetic information as a cause of mammalian aging
#5What makes me somehow believe in the information theory of aging is that old people look "noisy".
Sure, but "ageing is a result of increasing entropy" is pretty much the same as saying that ageing is caused by the passage of time.
The interesting part here is that they narrow down which loss of information is important.
Re: Loss of epigenetic information as a cause of mammalian aging
#6I think its a cool theory and seems the most reasonable from all the other theories of aging. However I am a bit disappointed when I only see David's name on every paper published on this topic. Why dont other institutions start similar studies to verify this claim?
Re: Loss of epigenetic information as a cause of mammalian aging
#7What makes me somehow believe in the information theory of aging is that old people look "noisy".
Sure, but "ageing is a result of increasing entropy" is pretty much the same as saying that ageing is caused by the passage of time. The interesting part here is that they narrow down which loss of information is important.
Inevitable entropy increasing is a red-herring in the presence of free-energy, no? What you point out though is very interesting, what would it take to inject energy into conserving this information? And what would its effects actually be? Could you pause aging, reverse it? Now this gets hairy, what happens to society? I dare say not everyone can live forever. What are the consequences of having a select few continuing to live youthfully and reproducing? Can we wind up with a loss of genetic diversity in our species? Entropy strikes again!
Re: Loss of epigenetic information as a cause of mammalian aging
#8What makes me somehow believe in the information theory of aging is that old people look "noisy".
Sure, but "ageing is a result of increasing entropy" is pretty much the same as saying that ageing is caused by the passage of time. The interesting part here is that they narrow down which loss of information is important.
Increasing entropy in a system can be avoided with an external energy source.
Re: Loss of epigenetic information as a cause of mammalian aging
#9Earlier quoted context omitted.
Sure, but "ageing is a result of increasing entropy" is pretty much the same as saying that ageing is caused by the passage of time. The interesting part here is that they narrow down which loss of information is important.
Increasing entropy in a system can be avoided with an external energy source.
So I should thank my uncle for introducing me to licking 9V batteries?
Re: Loss of epigenetic information as a cause of mammalian aging
#10I think its a cool theory and seems the most reasonable from all the other theories of aging. However I am a bit disappointed when I only see David's name on every paper published on this topic. Why dont other institutions start similar studies to verify this claim?
I assume the time to publish is too long, and the research too expensive. Aging takes time. Hopefully this changes soon.