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Long term high-fat diet expands waistline and shrinks brain

unisa.edu.au

1–10 of 17 posts

Re: Long term high-fat diet expands waistline and shrinks brain

#3
In mice.

Also, without being able to see the actual paper at this point, there's no way to draw any conclusion from this whatsoever. After all, how do we know what composed this high-fat chow fed to the mice? I've seen other studies where both the control group and the high-fat group were fed chow that contained substantial amounts of sucrose.

Re: Long term high-fat diet expands waistline and shrinks brain

#4
How does this fit in with the fact that high-fat low carbohydrate diet is used to help treat conditions such as epilepsy? I'm talking about the ketogenic diet here. Seems they omit the high-carb part in "high-fat diets". Do mice have similar metabolism to humans? I know they're used to study a lot of things before human trials, are our metabolisms similar? If you're low-fat high-carb you go into ketosis. Do mice do that as well?

Re: Long term high-fat diet expands waistline and shrinks brain

#5

In mice. Also, without being able to see the actual paper at this point, there's no way to draw any conclusion from this whatsoever. After all, how do we know what composed this high-fat chow fed to the mice? I've seen other studies where both the control group and the high-fat group were fed chow that contained substantial amounts of sucrose.

Also, in some studies a high fat rat diet is 50% carbs and 50% fat

Re: Long term high-fat diet expands waistline and shrinks brain

#6
post #4

How does this fit in with the fact that high-fat low carbohydrate diet is used to help treat conditions such as epilepsy? I'm talking about the ketogenic diet here. Seems they omit the high-carb part in "high-fat diets". Do mice have similar metabolism to humans? I know they're used to study a lot of things before human trials, are our metabolisms similar? If you're low-fat high-carb you go into ketosis. Do mice do t…

> If you're low-fat high-carb you go into ketosis.

Is that backwards?

Re: Long term high-fat diet expands waistline and shrinks brain

#7
post #4

How does this fit in with the fact that high-fat low carbohydrate diet is used to help treat conditions such as epilepsy? I'm talking about the ketogenic diet here. Seems they omit the high-carb part in "high-fat diets". Do mice have similar metabolism to humans? I know they're used to study a lot of things before human trials, are our metabolisms similar? If you're low-fat high-carb you go into ketosis. Do mice do t…

> If you're low-fat high-carb you go into ketosis. Is that backwards?

Yes, yes it is

Re: Long term high-fat diet expands waistline and shrinks brain

#9
post #5

In mice. Also, without being able to see the actual paper at this point, there's no way to draw any conclusion from this whatsoever. After all, how do we know what composed this high-fat chow fed to the mice? I've seen other studies where both the control group and the high-fat group were fed chow that contained substantial amounts of sucrose.

Also, in some studies a high fat rat diet is 50% carbs and 50% fat

By mass or calorie?
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