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A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

cdc.gov

1–10 of 133 posts

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#4
post #2

I wonder what the implications for antibiotic-resistance might be for widespread usage at such a low dosage?

Doesn't seem like it would be widespread usage given the checklist they provide. Title is a little misleading; it's not just "a doxy a day keeps the lyme disease away!" or similar.

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#5
post #2

I wonder what the implications for antibiotic-resistance might be for widespread usage at such a low dosage?

The article is about prophylactic use in persons who have had a tick removed that was attached for more than 36 hours. It would have no impact on levels in the tick population (as it's given after the tick is removed) and should have no impact in the human population (considering how low the proportion of people with ticks attached for more than 36 hours is)

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#7

"may be used to reduce the risk of acquiring Lyme disease after the bite of a high risk tick bite." This seems slightly different than outright 'preventing' as the title currently says.

from another source:

> The authors concluded that a single 200-mg dose of doxycycline given within 72 hours of a bite from an I. scapularis tick was 87 percent effective in preventing the development of early Lyme disease

https://www.aafp.org/pubs/afp/issues/2002/0215/p714a.html

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#8
post #5
post #2

I wonder what the implications for antibiotic-resistance might be for widespread usage at such a low dosage?

The article is about prophylactic use in persons who have had a tick removed that was attached for more than 36 hours. It would have no impact on levels in the tick population (as it's given after the tick is removed) and should have no impact in the human population (considering how low the proportion of people with ticks attached for more than 36 hours is)

I'm not worried about tick-borne diseases in this context (completely agreed with your point there), but rather all the other things that doxycycline and similar drugs are used against.

https://en.wikipedia.org/wiki/Tetracycline_antibiotics

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#9
post #6

interesting that it is for >= 36 hours. i always heard 24, so i'm grateful for the extra half day of buffer. though i also no longer live in the northeast, i hear it's a wicked bad year for ticks.

mid-atlantic US checking in. We've had three cases in our family since 2010.

it's always a bad year for ticks, it feels like :(

still hopeful for a vaccine, though. https://www.cdc.gov/lyme/prev/vaccine.html

Re: A single prophylactic 200mg dose of Doxycyline prevents Lyme disease

#10
Had to take doxycycline for 2 weeks after a tick bite. Man does that stuff destroy your digestive system. 7 years ago was on a date, just casually walking down the street. Coughed a couple times for no particular reason but my doxycycline lined stomach didn’t like that and boom projectile vomiting. Luckily he thought it was funny/ felt bad for me.
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