BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
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BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
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Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#2Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#3Impressive if true, although I am very sceptical of the results. The real test is to put their neck on the line and predict/warn of the next significant variant. If the authors are not willing to do this, I doubt that the algorithm is useful.
As a side note, the first author on this paper is the CEO of InstaDeep. I see it as a red flag that the CEO of a 150+ person company would put themselves as first author on this paper. Perhaps I'm unfairly judging and the CEO really was the lead contributor to the study.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#4The blog post from the InstaDeep site:
https://www.instadeep.com/2022/01/biontech-and-instadeep-dev...
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#5I'm all for stopping new variants of COVID. Why in the world do we have a treatment for COVID that intentionally creates mutations in COVID https://en.wikipedia.org/wiki/Molnupiravir ? I'm not a doctor but it seems pretty clear to me that Molnupiravir creates a great environment for new variants to arise (along with cancer, but that's another issue).
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#6Regardless of the specifics here, I'm pleased and envious of being reminded that some people have meaningful jobs that actually make a difference.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#7I'm all for stopping new variants of COVID. Why in the world do we have a treatment for COVID that intentionally creates mutations in COVID https://en.wikipedia.org/wiki/Molnupiravir ? I'm not a doctor but it seems pretty clear to me that Molnupiravir creates a great environment for new variants to arise (along with cancer, but that's another issue).
How does it seem clear to you? What's the mechanism through with Molnupiravir creates new CoV mutations?
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#8I'm all for stopping new variants of COVID. Why in the world do we have a treatment for COVID that intentionally creates mutations in COVID https://en.wikipedia.org/wiki/Molnupiravir ? I'm not a doctor but it seems pretty clear to me that Molnupiravir creates a great environment for new variants to arise (along with cancer, but that's another issue).
How does it seem clear to you? What's the mechanism through with Molnupiravir creates new CoV mutations?
GP explicitly referenced the drug's Wikipedia page:
> "The emergency use authorization was only narrowly approved (13-10) because of questions regarding efficacy and concerns that molnupiravir's mutagenic effects could create new variants that evade immunity and prolong the COVID-19 pandemic."
The quote above has its own citations in the Wikipedia page posted by GP.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#9I'm all for stopping new variants of COVID. Why in the world do we have a treatment for COVID that intentionally creates mutations in COVID https://en.wikipedia.org/wiki/Molnupiravir ? I'm not a doctor but it seems pretty clear to me that Molnupiravir creates a great environment for new variants to arise (along with cancer, but that's another issue).
How does it seem clear to you? What's the mechanism through with Molnupiravir creates new CoV mutations?
He linked to a source that contains that claim, it includes several sources for that specific claim.
It's unclear why that is relevant in this thread though.
Re: BioNTech-InstaDeep Early Warning System to Detect High-Risk SARS-CoV-2 Variants
#10Impressive if true, although I am very sceptical of the results. The real test is to put their neck on the line and predict/warn of the next significant variant. If the authors are not willing to do this, I doubt that the algorithm is useful. As a side note, the first author on this paper is the CEO of InstaDeep. I see it as a red flag that the CEO of a 150+ person company would put themselves as first author on this…
> As a side note, the first author on this paper is the CEO of InstaDeep. I see it as a red flag that the CEO of a 150+ person company would put themselves as first author on this paper. Perhaps I'm unfairly judging and the CEO really was the lead contributor to the study.
Authors on scientific papers are ordered by name, so whoever's name is first is pure coincidence.