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Psilocybin Produced in Yeast

phys.org

1–10 of 214 posts

Re: Psilocybin Produced in Yeast

#4
post #2

Realistically, I know this will be used to make pills. But the first thing I thought when I saw the headline was, "Wow. That's some interesting beer."

I mean it sounds like if you could get your hands on this yeast you could actually make psychedelic beer (or bread).

Re: Psilocybin Produced in Yeast

#5
> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...”

This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly controlled settings and then testing for potency?!

As someone who’s recently had very positive experiences with both large/small doses of magic mushrooms, it’s disheartening to see us remake the mistakes of the past by trying to over-engineer something from nature. IMO, the optimum approach would be to have humility and simply be stewards of this wonderful gift. There is no reason That psilocybin shouldn’t be administered in its most common form, as it has been for thousands of years, other than it would be harder to profit off of.

Re: Psilocybin Produced in Yeast

#6
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Also, since we already have 4-aco-dmt (which is virtually identical to psilocybin), so there's no real reason to extract.

Re: Psilocybin Produced in Yeast

#7
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Dosing is far easier in pill form regardless?

Re: Psilocybin Produced in Yeast

#8
Psilocybin may be an underrated chemical precursor. 4-substituted indoles are notoriously difficult to synthesize. Psilocin is a rare example of a natural one. (LSD is another.) For example, a milliliter of 4-bromoindole costs a whopping $75:

https://www.sigmaaldrich.com/catalog/product/aldrich/524336?...

Presumably this technique could produce psilocybin for much less than $75 per milliliter.

Re: Psilocybin Produced in Yeast

#9
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Dosing is far easier in pill form regardless?

You can make capsules from ground up mushrooms very easily.

Re: Psilocybin Produced in Yeast

#10
post #5

> "It's unfeasible and way too expensive to extract psilocybin from magic mushrooms and the best chemical synthesis methods require expensive and difficult to source starting substrates...” This is one of those situations where I feel like we (humans) are approaching it all wrong. Why over complicate it by trying to “extract” the psilocybin instead of treating it like marijuana and growing the mushrooms in highly con…

Hey, drug on wars still exists in the world. You can get excessive jail time just for having some (regardless of quantity) marijuana on you - and that is in "western" country. It was not so long ago that "marijuana had no possible medical application" and was scheduled as a class A drug in UK (and I think, still is). There is a lot of stigma, and decades of bad science, propaganda, and manufactured hatred run deep. Research is difficult, if at all possible because excessively harsh legislation. And who benefits?.. criminal cartels and enforcement agencies. This is also why scientists go such extreme lengths to create psychoactive mimics ("legal highs") - so they can research the stuff that is at least similar without going to jail. It's a fucked up world, my friend.

It's not the scientists' approach that is wrong, it's the legislators...

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