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U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

hhs.gov

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Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#3
My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ.

I'm for decriminalization and legalization but at the core we need funding for long term studies to better understand marijuana's effects. Unfortunately the politicization of marijuana has led it, similar to guns, to be woefully understudied as a topic of public health in the US.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#5
> Edible marijuana takes time to absorb and to produce its effects, increasing the risk of unintentional overdose

No citation for this. Do they mean a larger than intended dose or a dose that results in a serious toxic reaction or death?

Better source:

Median lethal THC dose for a 70kg human estimated to be 4g [0], which is slightly over 1300 full joints (at 3mg per joint) [0]. I won't link them here, but a cursory web search showed me stores claiming to sell edibles with up to 1000mg of THC.

Also a good read [1] [2]

0. https://www.tandfonline.com/doi/abs/10.3109/0095299930900161...

1. https://www.nature.com/articles/srep08126

3. https://www.cbc.ca/news/canada/calgary/cannabis-overdose-tox...

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#6
post #3

My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ. I'm for decriminalization and legalization but at the core we need funding for long term…

> as a result developed schizophrenia

I'm sorry about your brother, but I want to point out this is anecdotal. Can cannibals lead to psychosis in people who are prone to it genetically, or are people who start experiencing delusions, bipolar and schizo-effective conditions just likely to escape using alcohol and marijuana? The exact cause/effect conditions here are a big unknown.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#7
another risk factor for cannabis users is contamination by pesticides. many of the illegal grow sites in California national forests have been contaminated by Carbofuran, a banned pesticide. this chemical is applied to the plants. these operations still supply a large fraction of consumer marijuana demand. if you're gonna toke, know your weed supply chain.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#8
post #3

My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ. I'm for decriminalization and legalization but at the core we need funding for long term…

This. I am all for legalization but it’s not a safe drug. Induced schizophrenia by weed can be a thing if you carry a specific gene.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#9
post #5

> Edible marijuana takes time to absorb and to produce its effects, increasing the risk of unintentional overdose No citation for this. Do they mean a larger than intended dose or a dose that results in a serious toxic reaction or death? Better source: Median lethal THC dose for a 70kg human estimated to be 4g [0], which is slightly over 1300 full joints (at 3mg per joint) [0]. I won't link them here, but a cursory w…

There are no known deaths purely from marijuana overdose.

Re: U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

#10
post #3

My brother smoked heavily during his teens and as a result developed schizophrenia / substance induced psychosis. It was generally terrifying to see him unable to complete thoughts and lose his train of thought. He's fine now but I definitely wouldn't be surprised if you told me those years knocked a couple of points off his IQ. I'm for decriminalization and legalization but at the core we need funding for long term…

How much of that was due to smoking pesticides on the product, and how much of it (if any) was due to the product itself?

Until we have proper studies on this (which is hard, because of the current federal drug classification), it is impossible to tell.

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