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Magnesium and major depression (2011)

ncbi.nlm.nih.gov

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Re: Magnesium and major depression (2011)

#4
post #3

Take some hart burn medicine and you get all the magnesium you can handle.

Heart burn meds are often Mg Oxide or sulfate, which isn't that well absorbed. [1,2] for anxiety and depression, Mg Citrate works well, as does Mg Glycinate [3]

Just a heads up.

[1]http://www.kumc.edu/school-of-medicine/family-medicine/integ...

[2]https://www.ncbi.nlm.nih.gov/m/pubmed/2407766/

[3] https://www.psychologytoday.com/us/blog/evolutionary-psychia...

Re: Magnesium and major depression (2011)

#6

Poor man's TLDR: we're not sure yet, but consider taking magnesium supplementation to help with or prevent MD. The downside of light Mg supplementation seems trivial, and the upside could be strong.

Magnesium also promotes muscle relaxation and “calms the brain”. Here in Switzerland it’s commonly taken over-the-counter. I had never heard of it as a supplement in the US.

Re: Magnesium and major depression (2011)

#7

Poor man's TLDR: we're not sure yet, but consider taking magnesium supplementation to help with or prevent MD. The downside of light Mg supplementation seems trivial, and the upside could be strong.

Mg deficiency is also implicated in some cardiac arrhythmias and supplementation has been shown to help.

Re: Magnesium and major depression (2011)

#9
Needs a [2011] and some scepticism: Many people have tried Magnesium because it is cheap and available without prescription. If it were as effective as "success in 220 out of 250 cases" claims, that would show up.

The 220 of 250 claim also doesn't fit with "as effective as the tricyclic antidepressant imipramine". No antidepressant is 90% effective.

Re: Magnesium and major depression (2011)

#10

Needs a [2011] and some scepticism: Many people have tried Magnesium because it is cheap and available without prescription. If it were as effective as "success in 220 out of 250 cases" claims, that would show up. The 220 of 250 claim also doesn't fit with "as effective as the tricyclic antidepressant imipramine". No antidepressant is 90% effective.

Most cheap magnesium is magnesium carbonate which is least effective and causes diarrhoea (should be taken with calcium to prevent that). Magnesium aspartate is sometimes prescribed as "working one", but can be neurotoxic (according to this paper).
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