Evidence of the body’s waste system in the human brain
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Re: Evidence of the body’s waste system in the human brain
#2Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products).
Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
Re: Evidence of the body’s waste system in the human brain
#3Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
You're probably thinking of the so-called "glymphatic system" that was in the news a few years back.
https://en.m.wikipedia.org/wiki/Glymphatic_system
Re: Evidence of the body’s waste system in the human brain
#4Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
> being one of the reasons we need sleep
Jellyfish have no brain, but also sleep. So that can't be the reason. (It might happen then anyway, but it's not the fundamental reason.)
Re: Evidence of the body’s waste system in the human brain
#5I hope this will lead to new targets for neurodegenerative proteinopathies.
Re: Evidence of the body’s waste system in the human brain
#6Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
You're probably thinking of the so-called "glymphatic system" that was in the news a few years back. https://en.m.wikipedia.org/wiki/Glymphatic_system
Yep, that's exactly the one I was thinking of. Thank you!
Re: Evidence of the body’s waste system in the human brain
#7Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
> being one of the reasons we need sleep Jellyfish have no brain, but also sleep. So that can't be the reason. (It might happen then anyway, but it's not the fundamental reason.)
[deleted]
Re: Evidence of the body’s waste system in the human brain
#8Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
> being one of the reasons we need sleep Jellyfish have no brain, but also sleep. So that can't be the reason. (It might happen then anyway, but it's not the fundamental reason.)
We don’t need to sleep, but our body will put us to sleep. There is no clear answer as to why we sleep. But one acceptable theory is our brain “understands” sleeping is going to help functioning. During sleep our immune system finally has the opportunity to clean up waste. The 2017 Nobel Prize winners for Medicine and Physiology discovered there are genes famously work as “inner clock”, and they think these genes are responsible for all the routines in our body.
But fundamentally we still do not have an absolute answer to why we sleep, just like we have several theories on why we dream. However, I believe whatever theories exist for why we sleep and why we dream, they are union of a bigger theory, not mutually exclusive.
[1]: https://www.google.com/amp/s/amp.theguardian.com/science/201...
[2]: https://www.nobelprize.org/nobel_prizes/medicine/laureates/2...
Re: Evidence of the body’s waste system in the human brain
#9Interesting stuff, though I could have sworn I'd seen something similar before, to do with the waste draining being one of the reasons we need sleep (i.e. the body needs time to drain the accumulated waste products). Anecdotally, whenever I've had that droopy-eyelids nodding off sensation, when it passes it has always felt like the tiredness is literally draining from my brain.
> being one of the reasons we need sleep Jellyfish have no brain, but also sleep. So that can't be the reason. (It might happen then anyway, but it's not the fundamental reason.)
You guys keep saying that silly myth.
They don't have a BRAIN but they have nervous system. A nervous system creates waste and that waste needs to be reclaimed. What's a brain? An exotic collection of neurons... that create waste.
http://neurodojo.blogspot.com/2009/05/jellyfish-nervous-syst...
>Instead, jellyfish have a ring nervous system, located along the margin of the bell. There is definitely a concentration of neurons in that location (although it contains relatively few neurons compared to other animals). Plus, those neurons do serve as an active relay and processing station for sensory and motor activity. Those are two of the main things that central nervous systems do, so there seems to be no good reason to deny that jellyfish have a central nervous system. (Picture from Mackie and Meech, 2000.)
https://en.wikipedia.org/wiki/List_of_animals_by_number_of_n...
Jellyfish: 5,600 neurons.
Box jellyfish: 8,700-17,500 neurons.
Human: 86,000,000,000 neurons.
Notice jellyfish do not have "zero" neurons.
Further, from the wiki: "Not all animals have neurons; Trichoplax and sponges lack nerve cells altogether."
https://www.quora.com/Do-sponges-sleep
"Do sponges sleep?"
"As noted by others, sponges lack nervous systems, [...] sponges don't have nerve cells at all. So NO they don't 'sleep" in any manner similar to other animals."
Re: Evidence of the body’s waste system in the human brain
#10Earlier quoted context omitted.
You're probably thinking of the so-called "glymphatic system" that was in the news a few years back. https://en.m.wikipedia.org/wiki/Glymphatic_system
Yep, that's exactly the one I was thinking of. Thank you!
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