This type of software, is just a bandaid and really doesn't work very well (though it can work better with headphones). Properly thought out and tuned acoustic work is what is needed.
I am lucky enough to have a spare room in my house, and set out to build a studio (an almost life-long dream) and decided that I didn't want to compromise on the acoustics and spent some time looking into the subject. In the end I built it myself with a huge amount of acoustic treatment (lost a large amount of the volume room), but more that that I enlisted the help of a professional who could do the maths and help with not just the trapping but also the panels that are needed. In the end after I built it was also tuned with DSP by the professional, has what you would normally call 4-way speakers with the subwoofers going to a higher frequency than most would consider normal and even the desk was specifically chosen
to not cause a problem for the listening environment. The difference between this and something like Sonarworks (commercial software that I tried for a laugh beforehand) cannot be overstated. It's basically flat between 23hz (slightly rises at 20hz I believe) and 20Khz - we actually tuned in a more natural response curve.
It's still a home studio because it's in my home and I don't do anything commercial with it, but it's pretty much mastering grade, all with materials that are available in a builders yard and the special sauce, someone that knew what they are doing. Not everyone has the room or space to do this, but most people can build some bass traps and something to tame first point reflections.