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Show HN: Refractify – Optical software against myopia

refractify.io

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Re: Show HN: Refractify – Optical software against myopia

#51

Earlier quoted context omitted.

ReducedLens is absolute quackery! This is why I hate myopia discussions. Myopia is not reversible, if you think it is, you don't understand what axial elongation actually means.

Are there any publications you can point me to that show the techniques there are ineffective?

Your eye's axial elongation is caused by the eye growing longer, which means *more cells in the eye.* Your eye grows in response to visual stimulus, without the brain's involvement. Your eye shape physically changes by *extra cell production* to cause axial elongation. This process is called emmetropization. It's extremely well understood. Peripheral defocus lenses and low dose atropine are proven to work in reducing speed of myopia progression because they reduce the stimulus causing the eye to elongate. Let me say that again: The way axial elongation happens is well understood, and we have known interventions to interfere with the growth stimulus. We know how to control myopia.

There is no known way to reverse this growth process. The only scientifically proven intervention for reducing myopia is surgery. There is no concrete evidence of for any other intervention, nor is there any other known mechanism for causing the eye to reshape itself to reduce axial elongation. For the eye to become truly less elongated, your body has to break down the extra cells in the eye and cause reshaping. An example of this is wound healing: your body breaks down the ECM with TMP activation. We know how the *opposite* works, the eye grows in response to overfocus to find focus. When too much is in focus in your peripheral vision (near work, holding things close to your face), the eye thinks it's over-focusing, and physically grows to find focus. Near work is the issue. Outdoor light probably isn't the issue, it's probably because when you're outside, you're not doing near work.

For those who do experience improvements, it's not from changes to the cellular structure of the eye. There are multiple temporary known mechanisms for your eye changing focus. One of them is the thickness of the choroid, a tissue layer in the back of the eye. Another is possibly muscular, your axial elongation is known to show variable diopters during the day (maybe +-0.25 but I don't know the actual variance). Studies do show fast-acting axial elongation reduction (minutes to hours) in response to defocus, but this is obviously not from the eye reshaping itself, so this is obviously not reversing myopia, this is just changing temporary variables in the eye. For the majority of people who report "reversing" myopia, it is usually a negligible change (2 diopters) which is easily explainable with these mechanisms, rather than the false belief it's actually changing the elongated eye shape. Ortho-K is another known temporary / superficial intervention.

The burden of proof of truly changing the axial elongation and fundamental structure of the eye cells is on you, and on the EndMyopia quacks. There are no studies that demonstrate significant diopter changes that would demonstrate the eye is reshaping itself to actually reverse myopia. You are welcome to find the studies on the Bates method and wearing undercorrected lenses yourself, they don't work and possibly make things worse.

Re: Show HN: Refractify – Optical software against myopia

#52

Earlier quoted context omitted.

Are there any publications you can point me to that show the techniques there are ineffective?

Your eye's axial elongation is caused by the eye growing longer, which means *more cells in the eye.* Your eye grows in response to visual stimulus, without the brain's involvement. Your eye shape physically changes by *extra cell production* to cause axial elongation. This process is called emmetropization. It's extremely well understood. Peripheral defocus lenses and low dose atropine are proven to work in reducing…

Ok, here's proof of axial length changing following application of the method for years:

There was a member on the forums who was measuring his axial elongation while at the same time applying the reduced lens method. His result is shown in the following plot.[0] It is a significant improvement that can't be ignored, and can't be explained by day to day fluctuations or measurement error. So we know that at least some level of axial elongation can be reversed, and the idea is not complete quackery.

Also the reduced lens method has nothing to do with the Bates method, or undercorrection that leads to blur adaptation.

> "The only scientifically proven intervention for reducing myopia is surgery"

Which surgery reduces myopia? If you're thinking of LASIK then it doesn't change axial elongation.

[0] : https://i.imgur.com/J7WCNfY.png

Re: Show HN: Refractify – Optical software against myopia

#53

Earlier quoted context omitted.

Your eye's axial elongation is caused by the eye growing longer, which means *more cells in the eye.* Your eye grows in response to visual stimulus, without the brain's involvement. Your eye shape physically changes by *extra cell production* to cause axial elongation. This process is called emmetropization. It's extremely well understood. Peripheral defocus lenses and low dose atropine are proven to work in reducing…

Ok, here's proof of axial length changing following application of the method for years: There was a member on the forums who was measuring his axial elongation while at the same time applying the reduced lens method. His result is shown in the following plot.[0] It is a significant improvement that can't be ignored, and can't be explained by day to day fluctuations or measurement error. So we know that at least some…

Great. I would love to be proven wrong. My partial blindness from myopia related diseases will likely progress to full blindness as I age. I would love to be shown my worldview is wrong. For example, I didn't know anything about relative light color refractive differences until this HN post. I hope that science discovers a previously unknown mechanism or method for reducing axial elongation.

I also wish that eye doctors knew about the existing evidence. I wish that all opthamologists knew how emmetropization worked, I wish all lenses were peripheral defocused, and I wish more eye doctors prescribed low dose atropine to children, because the evidence is clear. And I sincerely hope that more eye doctors get sued for not using these tools in their practice. Ignoring science based evidence of myopia control in a field where you only need to know about 20 things is negligence.

Proving axial elongation is reversible is not done by a n=1 pet theory forum post measured in a home lab by someone who doesn't know what their choroid is. These forums are filled with people with mild myopia, not high myopes, who are "just starting my journey!" or "I had a small correction and I plateaued!" but are still zealously telling everyone else how to reduce their myopia. n=1 is fine for Reddit tier evidence, but without studies, it doesn't matter.

Re: Show HN: Refractify – Optical software against myopia

#54
post #30

This is very cool and exciting. It seems like a good method to reduce the development of myopia. However, my understanding is that myopia is also simply age related. Discussions I've had recently were looking at the hardening of the lens as a factor. I've been trying to re-train my eye with an eye chart, and I've been surprised how after just a few weeks, my vision has gotten much clearer. Going from 20/40 to nearly…

Could you describe a bit more about how you've re-trained your eyes with an eye chart?

I downloaded a Snellen chart, and put it up on the wall. I practice twice a day. I read somewhere that you can also have a closer chart and a distance chart and to swap looking at each throughout the day.

Of course, you could memorize the letters, but that isn't really helping you. What you want to do is to focus on the blurry point, try to make out the letters. Over time, you'll slowly find that you are able to improve.

Previously, when I was younger, I just focused on getting outside more and trying to read signs that were far off in the distance, or ensure that I was looking at far distant objects regularly.

Re: Show HN: Refractify – Optical software against myopia

#56
post #55

What's the deal with why it isn't available on Firefox?

Applying multiple svg filters on top of each other in the needed order resulted in Firefox dropping the filters completely. I filed a bug for Firefox: https://bugzilla.mozilla.org/show_bug.cgi?id=1873644 As soon as it is fixed there will be a Firefox extension, and the live demo on the site will start working.

Re: Show HN: Refractify – Optical software against myopia

#58

Earlier quoted context omitted.

The Mac version is in progress.

How about Linux (Ubuntu, Mint)?

There's a section of the page that says:

>Get notified on future versions(including Linux) and clinical studies!

Re: Show HN: Refractify – Optical software against myopia

#59

Earlier quoted context omitted.

Your eye's axial elongation is caused by the eye growing longer, which means *more cells in the eye.* Your eye grows in response to visual stimulus, without the brain's involvement. Your eye shape physically changes by *extra cell production* to cause axial elongation. This process is called emmetropization. It's extremely well understood. Peripheral defocus lenses and low dose atropine are proven to work in reducing…

Ok, here's proof of axial length changing following application of the method for years: There was a member on the forums who was measuring his axial elongation while at the same time applying the reduced lens method. His result is shown in the following plot.[0] It is a significant improvement that can't be ignored, and can't be explained by day to day fluctuations or measurement error. So we know that at least some…

What is the source post of this? Is this chart really showing 0.1 millimeters of vitreous chamber depth change over 4 years? That almost sounds irrelevant, so maybe I'm missing something.
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