21–30 of 44 posts
The about page [1] is very interesting. "3. Providing a foundation for uploading research .... If it can be done for a worm, the next steps are to attempt a zebrafish, then a fruit fly, then a honeybee, then a mouse, then a dog, then a macaque monkey, then a chimpanzee, and, ultimately, a human. " -- that really fascinate me. Isn't that awesome? But ... "the philosophical assumptions fail, and human immortality throu…
The about page [1] is very interesting. "3. Providing a foundation for uploading research .... If it can be done for a worm, the next steps are to attempt a zebrafish, then a fruit fly, then a honeybee, then a mouse, then a dog, then a macaque monkey, then a chimpanzee, and, ultimately, a human. " -- that really fascinate me. Isn't that awesome? But ... "the philosophical assumptions fail, and human immortality throu…
The link in the sidebar offers a reasonable elaboration: http://nemaload.davidad.org/about/philosophy
Doing a nematode-version Turing test is one thing. You could even do it as a nematode in a Chinese box. But isn't there a flaw in comparing how a real nematode's brain reacts to light vs. a nemaload function to a specific computed wavelength of light energy? I think I'm not understanding something.
The about page [1] is very interesting. "3. Providing a foundation for uploading research .... If it can be done for a worm, the next steps are to attempt a zebrafish, then a fruit fly, then a honeybee, then a mouse, then a dog, then a macaque monkey, then a chimpanzee, and, ultimately, a human. " -- that really fascinate me. Isn't that awesome? But ... "the philosophical assumptions fail, and human immortality throu…
The jump from honeybee to mouse is enormous - much larger than any of the other jumps except chimpanzee to human. Maybe try lizard in between them.
These are massive efforts, and involve horrendous heaps of diligent busywork. This makes me the boring naysayer, but please don't be distracted by the startup-like appearance and the peculiar financing situation. It's possible but unlikely that the major obstacle here is simply the combination of available techniques!
Honestly, what I'm most curious about are his thoughts on model-driven interrogation of an in vivo system -- biologists, and even computational neuroscientists, are a bit too hesitant when it comes to letting computers find and test hypotheses. In the age of highly advanced genetic techniques (e.g., binary expression systems in Drosophila or zebrafish) and 2-photon imaging, the process of actually evaluating hypotheses has become a bit old-fashioned...
Sounds really interesting. You could try to secure additional funding for this project via Microryza ( http://www.microryza.com/ ), which is a kickstarter for scientific research.
Side note, I used to do work with CAD systems for simulating/building gene circuits. I can't wait until we move from open tools (Tinkercell, Biobricks, Genome Compiler, etc) to fully-modeled open platforms for organisms. Imagine having the latest build for E.Coli or C.Elegans, or a package manager to organize them, at your fingertips so that you can hack away at new designs. It makes you wonder, with so many people i…
Earlier quoted context omitted.
Side note, I used to do work with CAD systems for simulating/building gene circuits. I can't wait until we move from open tools (Tinkercell, Biobricks, Genome Compiler, etc) to fully-modeled open platforms for organisms. Imagine having the latest build for E.Coli or C.Elegans, or a package manager to organize them, at your fingertips so that you can hack away at new designs. It makes you wonder, with so many people i…
How is "Genome Compiler" an open tool? I hate those guys, it's not even an actual compiler. or open. If they wanted to do something useful, then yeah I would shoot for that package management concept.
The about page [1] is very interesting. "3. Providing a foundation for uploading research .... If it can be done for a worm, the next steps are to attempt a zebrafish, then a fruit fly, then a honeybee, then a mouse, then a dog, then a macaque monkey, then a chimpanzee, and, ultimately, a human. " -- that really fascinate me. Isn't that awesome? But ... "the philosophical assumptions fail, and human immortality throu…
The jump from honeybee to mouse is enormous - much larger than any of the other jumps except chimpanzee to human. Maybe try lizard in between them.
Personally, though, I'm limiting my scope to the worm (at least for now!). The particular path which is best to take beyond that is much less clear.
The about page [1] is very interesting. "3. Providing a foundation for uploading research .... If it can be done for a worm, the next steps are to attempt a zebrafish, then a fruit fly, then a honeybee, then a mouse, then a dog, then a macaque monkey, then a chimpanzee, and, ultimately, a human. " -- that really fascinate me. Isn't that awesome? But ... "the philosophical assumptions fail, and human immortality throu…
Do be careful when you get to lobsters.
Probably in the process of researching any of these topics a potential intern would gain a good understanding of the upcoming internship.
Sometimes I wish job interviews were laid out like this.