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Ask HN: What's the next big thing that few people are talking about?

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Re: Ask HN: What's the next big thing that few people are talking about?

#481
post #192

Earlier quoted context omitted.

ICE = Internal Combustion Engine for other non-native who wouldn't understand how a vehicle can work on ice

I thought he meant the German ICE trains and I was really worried for a second.

In Case of Emergency vehicles?

Re: Ask HN: What's the next big thing that few people are talking about?

#482
post #284

General purpose humanoid robots. They're kind of mainstream idea, but very few people talk about them or take them seriously. Humanoid robots will have an absolutely massive impact in very near future. Most people don't realize that with general purpose humanoid robots, labor becomes software. Labor becomes repeateable, testable, simulatable, modular, extensible, verifiable, etc. All things that apply to software wil…

> Tesla is showing their first humanoid robot prototype in September. I predict that Apple will soon follow.

Your predictions are off by a decade at least, and probably a lot longer. The extent of humanoid robots today is whatever billion dollar prototypes you see from Boston Dynamics and those security robots rolling around malls.

Re: Ask HN: What's the next big thing that few people are talking about?

#483
The end of the social networking era as we know it.

Many of the big giants from the 2000s - 2010s have pretty much peaked by now. TikTok is the thing everyone wants to be, but arguably its not a social networking app so much as a social entertainment app. You don't really connect with friends on it so much as with strangers. An endless stream of entertaining strangers. It's a lot more akin to YouTube than Instagram when you think about it.

That being said, I don't think the social networking era is completely over, its just that the focus is going to shift. After big social networking platforms come smaller communities that are probably isolated from the platform on Discord or some forum somewhere, or perhaps something new in the future. The platforms themselves won't go away, but more-and-more the dialogue will shift towards niche interests and community discovery.

Problem with these communities is that there's a very real risk that they could be "unmoored" from reality, especially if the user demographic leans towards loners. Prime example is 4chan. A lesser example would be someone on Twitter who exclusively uses it politically. I think this will only get worse over time, and possibly accelerate once AI gets involved. Using, I don't know, GPT-4 and DALL-E 3, you can create a seemingly thriving "community" filled with "people" who make hilarious memes and generate thought-provoking content, culminating in whatever world you want to live in. Possibly a very hateful one.

On a positive note, I think that the internet will become a somewhat more decentralized place again. I think that with the end of the social networking era we'll also see the end of the so called "walled garden" era of the internet. Making weird websites might just become cool again. VC money will still flow into "tech", but it'll mostly be towards AI or things that are more physical such as energy, climate, biotech, space, or maybe just physical consumer goods. The race to dominate the attention of the internet will be over.

Finally, there's "the metaverse". I think a lot of companies are going to try, and fail, to build VR Disneyland when what people really want to experience is a virtual city far larger than any real world city, with public squares to meet new people at and private, intimate worlds to share with your friends. Just seems far more likely that we'll instead wind up the internet all over again, only, you know, in VR, so just the internet really. If anything, I think a company might stake its claim in this future not by trying to build a platform, but by building tools.

Mind you, this is all still a long ways off I think, but in the present there are a lot of companies building 2D metaverses, which are basically community spaces.

https://sprout.place/ https://www.gather.town/

Re: Ask HN: What's the next big thing that few people are talking about?

#486

The stumble over abandonment of ICE vehicles. By 2030 (8 years from now) at least six manufacturers will have stopped making ICE vehicles entirely, and India claims it will ban the sale of ICE-only vehicles. By 2040 (18 years from now) over half of all new cars sold will be electric, and the UK and France claim they will ban the sale of ICE-only vehicles. However, there's still not a plan that makes all that sustaina…

What amazes me is how little we talk about hydrogen (H2) fuel cell vehicles. Because, unless we get a tremendous breakthrough in the next 5 years, electric battery vehicles will be a very big pain. -Batteries are terribly expensive (and prices are not going down as fast as expected) -Batteries degrade too fast -Batteries take too long to charge -Electricity prices are already going up terribly fast to take advantage…

The current world of electric cars is sort of like every smart phone before the iPhone came out. Then iPhone/Android hit, and the world was off to the races.

What is the "electric" car iPhone moment?

Re: Ask HN: What's the next big thing that few people are talking about?

#487

Preimplantation polygenetic testing. The idea is that, when doing IVF, you sequence the genome of all the embryos and implant the ones that you predict will have properties that you like. This already exists for monogenetic screening (for parents who don't want to pass on heritable diseases for their children, where those diseases are localized to one gene). But the idea here is that, by checking thousands of genes,…

> But the idea here is that, by checking thousands of genes, you can make predictions for things that start to be very relevant to parents, like attractiveness or height or intelligence. Personally, I think this interpretation of polygenic risk scoring is a crock of irreproducible shite. I don’t think it’s your fault, I think a lot of people in the field are shilling something they don’t have for grant money, and the…

> show me someone who can take a genome and predict adult height within a centimeter, then I’ll believe they have a snowball’s chance of predicting something as nuanced and varied as “attractiveness” or “intelligence”.

This has been done. Not to 1cm but ~3cm, and it has been reproduced by many labs all over the world

That said, most genetic prediction aren't targeting exact vales, but avoiding the worst outcomes, which is a lot easier.

Instead of saying this embryo will go grow to X cm, the claim is this embryo is 90% likely to grow to be taller than average.

Same for IQ. They don't predict the IQ, but decrease poor outcomes and increase high ones. Hell, we have had rough monogenic screening for IQ since the 1960s

https://arxiv.org/pdf/2101.05870.pdf

Re: Ask HN: What's the next big thing that few people are talking about?

#489

Preimplantation polygenetic testing. The idea is that, when doing IVF, you sequence the genome of all the embryos and implant the ones that you predict will have properties that you like. This already exists for monogenetic screening (for parents who don't want to pass on heritable diseases for their children, where those diseases are localized to one gene). But the idea here is that, by checking thousands of genes,…

[Gattaca]( https://www.imdb.com/title/tt0119177/ ) is about the long term consequences of this exact technology for society. In particular, the consequences for the children born naturally who don't benefit from this tech. They don't get any say in the decision, but end up heavily penalized, barred from certain jobs for "safety" reasons, aren't desirable partners... an underclass of society.

> the long term consequences of this exact technology for society

> They don't get any say in the decision, but end up heavily penalized, barred from certain jobs for "safety" reasons, aren't desirable partners...

you realize gattaca was fiction, right? and also

https://www.genome.gov/about-genomics/policy-issues/Genetic-...

Re: Ask HN: What's the next big thing that few people are talking about?

#490

I don't know about "big" in terms of a viral hit, but in terms of what will change in our day-to-day experience... Here are some wild guesses, mostly along the theme of a societal conversation about and re-thinking of "sustainability" on nearly all levels. * Robotic carts that follow you around when shopping in dense, pedestrian oriented areas and/or stores. Might go hand in hand with the rapid normalization of e-bik…

>apartment buildings with permacultured gardens growing their own food This has been tried (and proved wrong) countless times. The issue is that it needs a huge footprint, and space is something you don't have at large in apartment buildings.

I'm not familiar at all with this space. Is vertical farming a possible solution here?
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