Your enthusiasm warms my heart, cheers!
> ground-effect vehicles
I know of them a little. There may well be some applications for ground-effect in the devices I hope to build.
> bioengineer bacteria to eat plastic
Maybe so but that's outside my wheelhouse. :)
> you might be interested in concatenative languages like Forth, Factor, and colorForth.
Indeed! My "macro language" is a dialect of Joy: https://joypy.osdn.io/
> A good starting point or source of inspiration might be the Smalltalk and Lisp Machines from the past.
For sure they are inspirations, as well as the Oberon OS and Jef Raskin's "Humane Interface".
In re: Loper, yeah I love that guy (he's even more grumpy than I am for one thing.)
There are a lot of interesting projects and software out there that seem in the same or similar vein, such as Collapse OS or akkartik 's Mu.