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Ask HN: Who is hiring? (December 2025)

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Re: Ask HN: Who is hiring? (December 2025)

#362
YC W25 Biotech Startup Hiring – Build Programmable Therapeutic Vines

We’re EPIVINE—engineering self-replicating vines that deliver epigenetic age-reversal therapies as over-the-counter botanical supplements, bypassing pharma patents. Backed by YC, we’re turning plants into living pharmacies.

We’re hiring:

1. Senior Synthetic Biologist – Engineer dCas9-p300 nanostructures & optimize epigenetic editing. 2. Biomaterials Engineer – Design shape-memory alloy scaffolds that guide vine growth. 3. Computational Biologist – Model aging reversal (H3K9me3) and analyze epigenetic beacon data. 4. Full-Stack Biotech Dev – Build the IoT and data platform for our smart vineyards. 5. Head of Regulatory Strategy – Navigate FDA botanical supplement pathways and secure OTC status.

Why join? Founder-market fit (published epigenetic plant research), massive aging/wellness market, 3 provisional patents, and YC network. Located in South San Francisco.

*Apply:* Don’t send a resume. Pick a role, build something relevant in 48 hours, and email it to franciseni722@gmail.com.with the subject: `[Role] – [Your Name] – 48hr Build`.

We’re building the future where your garden treats disease. Help us grow it.

Re: Ask HN: Who is hiring? (December 2025)

#363
YASO / Full stack engineer / Product manager / Hybrid (London) / Full Time

We are building the operating system for international D2C brands going into China, managing the full cross-border ecommerce and social commerce stack - store operations, pricing, influencer partnerships, logistics.

D2C brands can compete and win in the market by abstracting away the infrastructure (to us) and focusing on reaching consumers.

We're based in London / Shanghai and are hiring for a PM and 2x full stack in London.

More details and apply here: https://apply.workable.com/yaso/?lng=en

Re: Ask HN: Who is hiring? (December 2025)

#364
Uniplay | Software Engineer (Mobile + Frontend Focus) | STOCKHOLM ONSITE/REMOTE HYBRID 3/5 | https://uniplay.io & Uniplay Business on App Store

We’re looking for a Software Engineer (Mobile + Frontend Focus) who can make Uniplay feel amazing in the hands of users. Smooth, playful, fast — the kind of app experience that people don’t just “use,” they enjoy. If you care about detail, motion, and flow, you’ll fit right in.

https://careers.uniplay.io/jobs/6689178-software-engineer-mo...

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Uniplay | Software Engineer (Backend-heavy) | STOCKHOLM ONSITE/REMOTE HYBRID 3/5 | https://uniplay.io & Uniplay Business on App Store

We’re looking for a Software Engineer (Backend Product Engineer) who loves building fast, scalable systems — the kind that don’t just “work” but elevate the product. If turning raw AI + data into real-time game logic sounds fun, you’ll probably love it here.

https://careers.uniplay.io/jobs/6685001-software-engineer-ba...

Re: Ask HN: Who is hiring? (December 2025)

#366
Moyai | Amsterdam, The Netherlands | FULL-TIME | ONSITE | Founding Product Engineer | 60k-80k + Equity

About the company:

• Technical founding team with relevant industry experience

• Backed by well-known European VCs (SpeedInvest + Galion.exe)

• Cloud native & freedom to shape our tech stack (TypeScript + Python)

Ideal candidate:

• Previous experience at start-up building tech at scale

• Thinks in terms of product functionality and customer demands not just features

• Familiar with API first practices and frameworks

• Bonus points if you are an ex-founder or have been first hire before

Moyai is an AI-powered agent monitoring tool for AI engineers looking to catch agent failures in production. Reach out to the founder directly: https://www.linkedin.com/in/rhommes/ or visit our website https://moyai.ai

*No agencies or recruiters, and we are unable to provide visa sponsorship

Re: Ask HN: Who is hiring? (December 2025)

#367
Nordic Semiconductor | Full Stack Developer (Python, C#, Rust, Go or C++.) | Full time | Oslo, Trondheim, Norway

Nordic Semiconductor is a global leader in wireless technology.

Are you passionate about building robust, scalable software solutions that make a real impact? We are seeking an experienced and motivated Full-Stack Software Developer to join our dynamic CAD & DevOps group in Design Enablement Department. You’ll have the opportunity to work on essential projects such as developing software for design automation and creating advanced tools that enhance EDA design flows. You will leverage modern technologies including Jenkins CI/CD, Docker, virtual machines, and cloud platforms, as well as data visualization tools like Plotly and Dash, to deliver robust and efficient solutions for our engineering teams.

Key responsibilities

    - Design, develop, and implement custom tools and applications across both frontend (web) and backend (database) environments.
    - Take ownership of service operations, ensuring reliability, performance, and continuous improvement of developed solutions.
    - Provide expert technical support for software products, acting as a primary contact for troubleshooting and resolution.
    - Document custom tools, create comprehensive how-to guides, and maintain clear procedures to facilitate seamless knowledge transfer and onboarding.
    - Collaborate closely with cross-functional teams, including engineers, product managers, and QA, to deliver high-quality software on schedule.
    - Contribute to code reviews, architectural decisions, and best practices to uphold strong software engineering standards.
Key Qualifications

    - M.Sc/B.Sc in Electrical Engineering, Computer Engineering, Computer Science, or a related field.
    - Strong programming skills in one or more of the following languages: Python, C#, Rust, Go or C++.
    - Experience with version control systems such as Git, Perforce, or Subversion, and familiarity with continuous integration/deployment (CI/CD) pipelines.
    - Comfortable working within a Linux/Unix environment, with proven ability to develop, debug, and deploy in these systems.
    - Excellent communication skills in English, both written and verbal, with the ability to convey complex technical concepts effectively.
    - Knowledge of database systems and REST APIs.
Please note that this position might be subject to a background check.

Apply here: https://nordictechjobs.com/jobs/3klpSfZY7b

Re: Ask HN: Who is hiring? (December 2025)

#368
Automattic | Remote | Full-time | Multiple roles

We’re looking for engineers to help us build, grow, and maintain products used by over a billion people each month across WordPress.com, WooCommerce, WordPress VIP, Jetpack, Tumblr, Beeper & Texts.com, Day One, Pocket Casts, and many more.

If you love the open web, open source, radical problem ownership, and simple over pure solutions, Automattic is probably the place for you.

Experienced Software Engineer

  * endlessly curious about how things work – infrastructure, language and libraries, product, and business
  * solves problems across any level of the stack, in any codebase
  * comfortable with using mostly PHP and JavaScript, no need to have serious experience with them
  * more info, salary, and how to apply 
https://join.a8c.com/enghn

Systems Engineer

  * removes friction between developers and shipping software
  * owns availability, performance, and security
  * shares code, experience, and knowledge both internally and externally
  * more info, salary, and how to apply 
https://join.a8c.com/syshn

Re: Ask HN: Who is hiring? (December 2025)

#369
Phoebe | Software Engineer | NYC (Chinatown/LES) | ONSITE

Phoebe is building the coordination layer for in-home care — one of the largest and fastest-growing labor markets in the US. Think Sim City and 24/7 logistics. We are growing crazy fast.

*Stack:* Python, TypeScript, Go/Rust, LLMs. Generalist role — you'll touch infra, product, and integrations.

*Team:* Second-time founders. I (Justin, CEO) sold my last company (YC S19) to Airtable. Backed great investors like Slow.

*Why join:* This is the ideal role if you want to start your own company in a few years. You'll learn the vertical AI playbook end-to-end: domain immersion, LLM-driven automation, and modern B2B GTM.

New grads welcome

Apply: https://jobs.ashbyhq.com/phoebe-work/74ada9e6-89e4-45b0-a54e...

Re: Ask HN: Who is hiring? (December 2025)

#370
Foundation Health | Remote (US) | Full-time Roles

We’ve just raised $20M in Series-A funding, and are accelerating all things product development as we build what’s next.

So, we’re hiring a number of Snr Software Engineers and Product Managers!

Our digital-first pharmacy and telehealth products are already powering major health systems. From automating communications and supporting patients on complex therapies - to digitizing workflows and payments, freeing care teams to focus on patients.

If you're passionate about building technology that directly improves patient experiences and outcomes, we’d love to speak with you!

Link to our careers page here: https://www.foundationhealth.com/careers

Thanks!

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