Our team is focused on building the tools necessary to visualize and interpret massive data sets of human genetic variation and functional genomic information. We have developed gnomAD (https://gnomad.broadinstitute.org), the world’s largest public reference dataset of human exomes and genomes. gnomAD has become one of the most widely used resources in the field, and is now the default reference database for virtually all clinical interpretation pipelines, as well as a standard analysis resource for a wide variety of genetic and biological studies. We estimate gnomAD has contributed to the clinical diagnosis of over 2 million patients with genetic disorders.
Your role will be to maintain the gnomAD browser, our open source web application for exploring gnomAD and related datasets, and develop new scientific functionality as we continue to grow to over 1 million human samples. You will work with a team of software engineers, computational biologists and clinical and research users to develop new features and visualizations that incorporate user feedback. Software engineering skills and an interest in user interface design and data visualization are key. Basic familiarity with genomics and DNA sequencing data is preferred, but not required. Most importantly, the ideal candidate will have enthusiasm for playing a critical role in a team-oriented project and learning new domains.
Minimum Requirements • Bachelors or Masters degree in Computer Science or related field or equivalent experience. • Experience with React, CSS, D3, GraphQL, Python. • Experience building web-based applications with a focus on quality and incorporating user feedback. • Highly collaborative attitude and ability to work well in a team setting. • Excellent communication skills. • Demonstrated attention to detail and analytical skills.
An ideal candidate could have any of the following: • Experience with Docker, Kubernetes, and a major cloud provider (Compute, Object Storage, IAM, Functions-as-a-Service) is a plus. • Experience with bioinformatics datasets and analyses is a big plus.
What we offer: • The chance to work on a project of international significance with a clear impact on families affected by rare genetic disorders. • The opportunity to share your work: many of our projects are open source, allowing you to showcase your contributions with the community. • Flexible remote work setting. Comprehensive benefits package.
Email Matt with resume and examples of previous work: msolomon@broadinstitute.org