For rooms with closed windows this stuff has in my experience a 100% success rate. (they always manage to get in somehow). Spray the room an hour before bedtime and it eradicates them. Guess it's similar to that stuff they spray on airlines. It is not a repellent but seems to actively kill them/render them unable to fly [Metofluthrin (Pyrethroid)] https://www.peacefulsleepsa.co.za/products/in-room-solutions...
Is there any known adverse effect for human health?
Though the instructions recommend ventilating the room a little after letting it settle, and I don't use it every night. Also I like to cover pillows before spraying.
It's very similar to the WHO recommended stuff used before and during flights - https://www.inchem.org/documents/ehc/ehc/ehc243.pdf