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Ask HN: Whom do you admire most?

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191–200 of 240 posts

Re: Ask HN: Whom do you admire most?

#191
post #64

Richard Feynman, because he showed me through his writing that we all, no matter our backgrounds, can be enthralled by the mysteries that surround us.

And that through charisma, you can become more famous than physicists that do better physics than you.

This is probably the most irritating comment I've seen on HN so far. Boo.

Re: Ask HN: Whom do you admire most?

#194
post #97

Earlier quoted context omitted.

That's a semantic argument. But what it means for aging is functionally the same; we're programmed to last a certain amount of time (when there is pressure) and when the pressure runs out... we break down. This is essentially the same as having a programmed break down time. Secondly, the argument on tarantulas does not rest on group selection at all. For any one male tarantula, he spreads his genes better by living 2…

So what if there's pressure? You argue that we must rewrite the source code -- so? Genetics = source code. So rewrite the source code.

We're too far away from understanding metabolism for that to be a realistic path to defeating aging in the near future.

The engineering approach of periodical repair seems like the only game in town.

Re: Ask HN: Whom do you admire most?

#195

Earlier quoted context omitted.

I conceded nothing. You're confusing investment on an evolutionary timescale with investment on an individual timescale. A male spider couldn't spontaneously decide to live another 6 years- it would take hundreds of thousands of years of evolution to achieve that. On a physiological level, increasing investment in the individual is difficult because so much about how we are built is developmentally fixed. You can't c…

Here's you've just shown that you have no idea what Aubrey and SENS are proposing. Maybe, like with Hofstadter's book, you've just "read the introduction" and then stopped? >We have no idea which genes contribute to aging, and how, and even how many. In all likelihood a simply astronomical number of genes would have to be altered to extend life. The whole point of SENS is that it DOESN'T try to fiddle with metabolism…

I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes.

Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest.

Re: Ask HN: Whom do you admire most?

#196

Earlier quoted context omitted.

Are you saying the end justifies the means?

If he is, then so did the mob revolutionaries. In fact, so did an HN poster right here in this thread: > The French Revolution was a step forward for humanity, no matter how messy it was. (from http://news.ycombinator.com/item?id=868344 ) The idea that the government should kill protesters might seem far too disrespectful of human life, but then, doesn't the word "messy" in the above quote evoke the same reaction?

That was a bit of verbal slight-of-hand, yes. I meant to imply that if you're willing to say "the ends justify the means" to kill people at Tiananmen Square, you don't have very good standing to criticize the French Revolution, because it's in fact easier to make that same argument about the French Revolution than it is about Tiananmen Square.

Re: Ask HN: Whom do you admire most?

#197

Earlier quoted context omitted.

It's true that individuals that live a little bit longer but have the same end of their reproductive period do no better in the gene pool. However, if it were advantageous to live longer, and those folks had a slightly longer reproductive period, then we would expect the lifespan-while-fertile to increase. Presumably this would also increase the overall lifespan as well, but really that's irrelevant to this discussio…

1) For most of history, humans and their ancestors didn't live very long. When you die at 30, there's not much selection for biological mechanisms to fix the problems that happen in someone who is 60. Natural selection is looking for genes that are good at reproducing themselves, not genes that are good at giving an individual long life. Once you have sexual reproduction in place, it is much simpler to just have lots…

>For most of history, humans and their ancestors didn't live very long.

Again, this is completely irrelevant to your argument. You can still evolve to live for a longer time while reproductively viable.

>Once you have sexual reproduction in place, it is much simpler to just have lots of offspring than to evolve even more repair mechanisms to extend life (at no great benefit to genes).

Again, it's all about trade-offs. For some organisms, it's most advantageous for them to reproduce as much as they can all in one go, and for others it makes sense to live a really long time and reproduce throughout that time period. See http://en.wikipedia.org/wiki/Semelparity_and_iteroparity

I own The Selfish Gene. And unlike you, I've read most of his actual scientific work as well, not just his work for the plebeian.

Re: Ask HN: Whom do you admire most?

#198

Earlier quoted context omitted.

Gorbechev did not kill the people gathered at the White House to demand their freedom from communism--he dissolved the Soviet Union and allowed liberalization. Deng may have not had the power to dissolve the communist system in China, but a recognition of the rights to free assembly and free political speech, combined with a concrete plan towards devolving power away from the Communist Party, would have been a better…

would have been a better option than killing people for asking for it. The people who died were people who refused to vacate a public area after occupying it for weeks, accumulating automatic weapons, defying orders to disperse, and burning buses and using them as blockades. These were not peaceful reformers, but power seeking revolutionaries, in the mold of revolutionaries that have destroyed nations for the past th…

I think it suffices to say that you have a lot of revisionist views. Not that you're wrong, per se, but that you go heavily against the common understanding of these events.

Re: Ask HN: Whom do you admire most?

#199
post #36

David Chappelle I hate that he has faded so much from the public eye. If you've never seen Dave Chappelle's Block Party get it and watch it, whether you enjoy hip-hop or not. If you've seen that and are otherwise interested his Inside the Actors Studio interview is pretty solid too. He is basically the type of role model I wish I could be someday.

Has his original script for Half Baked ever been released?

Re: Ask HN: Whom do you admire most?

#200

Earlier quoted context omitted.

I conceded nothing. You're confusing investment on an evolutionary timescale with investment on an individual timescale. A male spider couldn't spontaneously decide to live another 6 years- it would take hundreds of thousands of years of evolution to achieve that. On a physiological level, increasing investment in the individual is difficult because so much about how we are built is developmentally fixed. You can't c…

Here's you've just shown that you have no idea what Aubrey and SENS are proposing. Maybe, like with Hofstadter's book, you've just "read the introduction" and then stopped? >We have no idea which genes contribute to aging, and how, and even how many. In all likelihood a simply astronomical number of genes would have to be altered to extend life. The whole point of SENS is that it DOESN'T try to fiddle with metabolism…

> I know exactly what he's proposing. What I am saying is that it won't work, because aging has to do with developmentally fixed processes.

No you don't know "exactly" what he's proposing, and you don't understand what senescence is, as you've made clear many times here. I'm starting to feel this isn't very productive so we should probably stop this conversation.

> Sure, you can replace blood cells, but do you really think we can replace all your cells, including your neurons? If you want to go in for a complete brain transplant, be my guest.

Here you show again that you have no idea what SENS is proposing and you are making up strawmen. If you want to criticize something, please learn about it first.

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