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Ask HN: What startup/technology is on your 'to watch' list?

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Re: Ask HN: What startup/technology is on your 'to watch' list?

#162
post #113

Oxford nanopore sequencing. If a few problems can be figured out (mainly around machine learning and protein design), then it will beat every other biological detection, diagnosis, and sequencing method by a massive amount (no 10x, but more like 100x-1000x) It's hard to explain how big nanopore sequencing is if a few (hard) kinks can be figured out. Basically, it has the potential to completely democratize DNA sequen…

Can this be used to make faster corona virus tests ? If so maybe this is the time to Manhattan project this technology.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#163

Earlier quoted context omitted.

> C++ getting serious about safety. Buffer overflows and bad pointers should have been eliminated decades ago. We've known how for a long time. Would love some links to read over weekend. Thanks!

Things like: - std::string_view - std::span - std::unique_ptr - std::shared_ptr - std::weak_ptr (non owning reference to shared_ptr, knows when the parent is free'd) - ranges - move semantics - move capture in lambdas - std::variant - std::optional To be honest, learning rust has made me a better c++ programmer as well. Having to really think about lifetimes and ownership from an API perspective has been really neat.…

string_view, span and ranges are not conductive to safety, quite the opposite.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#166
post #99

Optogenetics [0]. Light changes electrical behavior in cells. AKA, point laser, neurons fire, I know kung-fu Memristors [1] Rebuilding the entire computer from EE basics. New 'color' added to EE spectrum, now computers process huge datasets on a watch battery CRISPR-CaS9 [2] Tricks bacteria used to keeps viruses out are pretty slick. Crtl-C, Ctrl-V for gene editing. $100B technology, easily. Strangely (encouragingly?…

I was excited for memristors in 2008 when HP announced they were right around the corner. They even built a new computer and a new OS to take advantage of memristors [1]. And then it never happened and no one has ever built one and it’s pretty much vaporware. I would be hesitant to trust anyone who says they’re anywhere close. It’s just not a technology that actually exists. [1] https://www.extremetech.com/extreme/20…

> They even built a new computer and a new OS to take advantage of memristors

I could be wrong but I think I remember reading somewhere they ran into patent infringement issues that they couldn't get around or something like that.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#167
post #25

Earlier quoted context omitted.

They'd be so much more successful, if "Install" button did not have this: wget https://cloudron.io/cloudron-setup chmod +x ./cloudron-setup ./cloudron-setup --provider [digitalocean,ec2,generic,ovh,...]

There's a cloudron 1-click image on Digital Ocean

Which, as a regular user, I don't understand when I see it.

Hell, I am a dev, and I still did not know that will let me create one quickly.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#168
post #132

Earlier quoted context omitted.

Tesla covering 3/6... stock price is definitely still low

I would never trust any self driving car that didn't use LiDAR. It's an essential sensor for helping to fix issues like this: https://www.youtube.com/watch?v=1cSw4fXYqWI&feature=emb_logo And it's not contrived since we've seen situations of Telsa Autopilot behaving weirdly when it sees people on the side of billboards, trucks etc.

Humans don’t need LiDAR to recognize billboards

Re: Ask HN: What startup/technology is on your 'to watch' list?

#169
post #132

Earlier quoted context omitted.

Tesla covering 3/6... stock price is definitely still low

I would never trust any self driving car that didn't use LiDAR. It's an essential sensor for helping to fix issues like this: https://www.youtube.com/watch?v=1cSw4fXYqWI&feature=emb_logo And it's not contrived since we've seen situations of Telsa Autopilot behaving weirdly when it sees people on the side of billboards, trucks etc.

I use autopilot every day. It stops for stoplights and stop signs now.

Re: Ask HN: What startup/technology is on your 'to watch' list?

#170
post #149
post #39

All the new products around WireGuard. I'm so tired of running VPNs. NAT traversal with protocols like STUN, TURN and ICE are going to allow point-to-point networks for all the clients. https://tailscale.com/ https://portal.cloud/app/subspace

Zerotier.com did this years ago and it works great.

I'm kinda sad for you - I've been using and advocating zerotier for a while (it's amazing and indispensable)...but in my circles the word 'wireguard' has got people excited, which (anecdotally) is benefitting tailscale and generating more hype around them than zerotier ever got. Hopefully a rising tide will lift all ships and you find a way to capitalise on it :)

(I prefer device-based zerotier-style access rather than login-based tailscale-style so that does sway me to zerotier...but I have to admit tailscale looks more polished, e.g. the screenshot of seeing other devices on the network. I get it's not a fundamental feature! But I can't help but appreciate it)

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