I am in my mid 40's and recently really noticed this. It felt like some of the teeth in the gears of my mind were worn down and things were slipping. After complaining about it to some peers I was informed this could be due to low testosterone so I went and had that tested. Apparently my testosterone level was that of a 70 year old man so I started testosterone replacement therapy. I can say that it is a complete gam…
You should investigate clomiphene citrate instead of testosterone directly. Clomid mutes the brains response to estrogen, the final feedback product of the testosterone cycle. This causes the body to produce more testosterone in the testes rather than front loading the cycle. The primary impact is your testes continue to function, while testosterone over time will chemically castrate you. This has been in use for 60…
Ask HN: Have you experienced decline in problem-solving skills? How to improve?
101–110 of 155 posts
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#102> 3. Has anybody found ways to improve their problem-solving skills? Or critical thinking? For me nothing ever beats running and the associated runners's high. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915811/ Probably you could analyze how so-called β-hydroxybutyrate is synthesized and eat precusors too before going.
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#103Earlier quoted context omitted.
>> I also drink and smoke plenty of weed, How is drinking weed an option, though?
Clearly I'm implying drinking alcohol and smoking weed . That said, I do think there is much work to be done in the cannabis cocktail area. Flavor wise there is a lot of unexplored possibility, the major challenge in this space is ensuring dosage is correct since the effects of each substance are felt on such different time lines. You don't want to start feeling a bit too drunk and realize that the weed hasn't even h…
all right, it seems though that your writing abilities were compromised by consuming alcohol and drugs. take care!
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#104Earlier quoted context omitted.
I'm pretty sure the FDA has never denied a drug use application because it's not patentable and that's just a conspiracy theory used by people pushing bogus treatments. If there's peer-reviewed research that it works, it would be prescribed without doctor shopping.
That’s not my point. It’s not patentable so it’s not commercially viable to go through the clinical trials process for something that’s basically free to produce. There is plenty of peer reviewed research, but not all doctors are aware of all research and testosterone replacement is widely marketed with very lucrative contracts to urologists. Feel free to read the research yourself https://www.ncbi.nlm.nih.gov/pmc/?t…
The FDA has a "new clinical investigation" program that is supposed to reward people running clinical trials. If you collect data showing efficacy of a new use of a previously-approved drug, you can "earn" the exclusive right to market it for that condition. Of course, someone has to actually do it...and the numbers don't always pan out.
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#105You're probably fine, but in addition to asking HN I'd recommend asking a doctor. After having surgery to remove the cancer, I also got a cognitive psych eval (several hours of testing) to establish a baseline. They were able to estimate the degree of decline I'd experienced due to surgery.
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#106One thing to check: Your hearing I went through a period of life in my late 30s where I felt I was getting stupider. I was struggling to pickup new concepts and get a handle on new situations quickly like I used to. I was made redundant during a 'restructure' and I strongly believe it was due to these issues I was dealing with. Several months after being made redundant I got my hearing checked - I had moderate hearin…
They are actually developing a drug which regrows the cilia in your cochlea which is pretty interesting [1]
[1] https://news.mit.edu/2022/frequency-therapeutics-hearing-reg...
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#10745 minutes of sustained aerobic exercise at least 3 times a week or every day ideally if you can fit it in. The method of action is probably neurogenesis in the hippocampus which is the brain region responsible for forming new memories but may also play a dominant role in associating information that the brain is already storing with new information aka problem solving. https://scholar.google.ca/scholar?q=aerobic+exe…
Cycling and swimming are the only ones that come to mind.
Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#108Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#109 1. Has anybody noticed their own cognitive decline? I'm 30 but am interested in experiences at all ages
I am 40yr old and still feel as mentally sharp as I was in my 20's but I have a lot less endurance, I used to be able to do deepwork for an almost infinite amount of time and nowadays I have 6 hours in a good day.Also when my wife had cancer my sharpness at work really dropped but it came back with her remission, stress is awful on the mind and the body.
2. Does anybody have a good way of testing their intellect or problem-solving periodically? This would at least help me keep track going forward
How much I am solicited to solve random problem at work is my indicator that I am still sharp. I have become a true full stack debugger and my stack start with the Fibre channels, between the SAN and the VMs hosts, and end in the browser ! 3. Has anybody found ways to improve their problem-solving skills? Or critical thinking?
Push-ups and reading as much technical material as I can. - Maybe my intellect has diminished from using alcohol and weed at an early age?
Alcohol and weed effect are temporary, unless you are a morbidly alcoholic - Maybe that I've been feeling a bit burnt out
Maybe! From experience burnout or intense stress has a dramatic negative effect on mental sharpness and motivation - Maybe I've gotten lazy and rely too much on, e.g., stackoverflow
I have no theory on that, except that I usually read manual before resorting to stack overflow. - Maybe medicine I take for mental health?
If your medicine has a significant anticholinergic component (paxil is one of the worst https://www.theseniorlist.com/medication/anticholinergic-dru... and that list is not extensive as they says), you have your culprit. - Insufficient sleep? I've been getting 6-7 recently but should probably be getting 7-9
I too sleep 6 to 7 hours a night but I feel like it the amount of sleep I need. If you feel that you need more sleep, do so ! - Maybe I've actually always been dumb and am only now realizing it!
I don't know you so I cannot say for sure but since you noticed your decline, it's unlikely!Re: Ask HN: Have you experienced decline in problem-solving skills? How to improve?
#110I am in my mid 40's and recently really noticed this. It felt like some of the teeth in the gears of my mind were worn down and things were slipping. After complaining about it to some peers I was informed this could be due to low testosterone so I went and had that tested. Apparently my testosterone level was that of a 70 year old man so I started testosterone replacement therapy. I can say that it is a complete gam…
You should investigate clomiphene citrate instead of testosterone directly. Clomid mutes the brains response to estrogen, the final feedback product of the testosterone cycle. This causes the body to produce more testosterone in the testes rather than front loading the cycle. The primary impact is your testes continue to function, while testosterone over time will chemically castrate you. This has been in use for 60…
Anastrozole or HCG (I forget which) should have prevented that