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zosima

HN member
Joined
Sun, Dec 02, 2007, 1:38 PM UTC
HN karma
947
Public activity
332 items

About zosima

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Recent public activity

  1. comment
    Comment #47935956

    This is ridiculous. Your meta review has like 80%-90% of the studies on semaglutide and liraglutide. When finding random effect per drug, they even say this: > Hence, the drugs eli…

  2. comment
    Comment #47931817

    But has only weak/moderate effect on weight loss compared to semaglutide, tirzepatide and retatrutide. Alzheimer is a lot more difficult to measure than weight and amyloid-beta in …

  3. comment
    Comment #47926959

    Yes, the new anti-amyloids are not a revolutionary therapy. But they do have a small but definite effect on disease-progression. (something which in a highly noisy indication like …

  4. comment
    Comment #47918734

    I wonder. Because if that was the question, why would they include anti-amyloid treatments that were never approved and are not part of any current treatment regimen and dilute the…

  5. comment
    Comment #47913060

    That systematic review is unfortunately severely flawed. They pooled the old anti-amyloid antibodies (which everybody agrees are inefficacious) and were never used outside clinical…

  6. comment
    Comment #47912222

    The genetic evidence that amyloid-beta is in some way causative of at least a subset of Alzheimer's disease is still extremely strong. The fact that amyloid-beta binding drugs like…

  7. comment
    Comment #46406111

    What has closing a government agency to do with free speech? Did you interpret the calls for the end of censoring and cancellations that all government agencies must continue to ex…

  8. comment
    Comment #46165967

    I wouldn't bother commenting if I were hallucinating figures. There is no figure 4a. If you look at figure 4 in the supplemental material you also see, per your expertise, that cov…

  9. comment
    Comment #46163505

    This is rather weird. Mortality in immediate connection with the vaccine (index time) would not have been captured here. I would hesitate to draw any conclusion from this paper. > …

  10. comment
    Comment #46163365

    I am speaking about what the paper shows. There are other sources of evidence for efficacy. This paper is not a very strong source of evidence for efficacy due to some obvious unco…

  11. comment
    Comment #46163232

    The reduction in all-cause mortality was independent of covid deaths. Which seems to suggest that there was big differences between the groups other than the vaccination. This of c…

  12. comment
    Comment #45277135

    Maybe those you call extremists are now the only sane people.

  13. comment
    Comment #45160906

    People who are poorer and have worse health are predisposed to live in cheaper dwellings, many of which are closer to roads and thus more noisy and with more air pollution. People …

  14. comment
    Comment #45026103

    This is not "everyone". I'd hope we'd fire anyone incompetent that's in a position to control the interest rate.

  15. comment
    Comment #45025852

    [flagged]

  16. comment
    Comment #45006322

    Yes, and so is big parts of Russia. Attacking one country is not the same as attacking a continent.

  17. comment
    Comment #45004000

    No, it's not. Social media is massively censored in many EU countries (and UK).

  18. comment
    Comment #45003993

    Russia has attacked Ukraine. Not Europe. Neither Ukraine nor Israel is part of EU or NATO.

  19. comment
    Comment #45003970

    Copyright is not censorship. Censorship is state/company mandated retraction or blockage of certain information. Copyright is state/company mandated blocking of certain forms of ex…

  20. comment
    Comment #45003318

    The vast majority of known blocks are missing on that list. It's in fact worse than no list as it gives the impression of transparency, where there isn't any.

  21. comment
  22. comment
    Comment #45002741

    That sounds really easy and straightforward. And yeah, committee decisions are well known for their technical excellence and far-sightedness.

  23. comment
    Comment #45002732

    Most of these are bad for most people. They do something superficially useful, but ultimately blocks innovation and small companies and so leads to large companies being protected …

  24. comment
    Comment #45002715

    Blocked by court or state. Private ISPs can't block sites. And this is true for almost all these legislations. They remove power from individuals and companies, while avoiding to l…

  25. comment
    Comment #44960229

    Yes, this is the narrative, supported by the funding agencies. Also, I'd like to add that it's almost always humans of European descent who are committing the dastardly deeds.