Viewing profile — seamossfet
seamossfet
HN member- Joined
- Sat, Jan 21, 2023, 6:55 PM UTC
- HN karma
- 292
- Public activity
- 45 items
- HN profile
- View on Hacker News ↗
About seamossfet
Talk to me about computational chemistry, bioinformatics, and molecular biology!
Recent public activity
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Comment #49012783
I don't know if I agree with the premise that having access to AI results in dulling human intellect. I feel like to get to Terry's level you need a combination of passion and apti…
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Comment #49012695
The big take away for is the fact that the ONLY reason why chatgpt was able to get to this counterexample was because of the knowledge of the person driving the conversation. I don…
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Comment #48799798
Nothing wrong with vibecoding a toy project.
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Comment #48040193
We're building a CAD for drug design, we often have to handle large and highly varied file formats. Protein structures, compounds, python scripts, lab notebook entries, instrumenta…
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Comment #48039489
Does this provide gitflow to handle conflicts from multiple agents touching the same file system or is it purely for single-branch sequential iterations on the filesystem? I have a…
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Comment #48025103
[dead]
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Comment #47876199
People often use "non-deterministic" to imply "unreliable" when that's not always the case. You can have an LLM that's clearly non-deterministic but also reliable for tasks.
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Comment #47768116
Great article, but your site background had me trying to clean my laptop screen thinking I splashed coffee on it.
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Comment #47722401
The hardest part about using agents to code for me has always been working in teams. When you can cut through huge parts of the code with a chainsaw, how do you review multi-thousa…
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Comment #47722116
This is why I built [AI slop tool]. [Self promotion link to my vibe coded startup with no users]
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Comment #47722064
A false dichotomy that segments typical replies into one of two groups. Group 1: A thinly veiled straw man that buckets everyone I disagree with, along with an attempt to appear as…
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Comment #47642027
The problem with models like this is they're built on very little actual training data we can trace back to verifiable protein data. The protein data back, and other sources of tra…
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Comment #47641927
This is awesome! The only limiter here is the resolution, I think this is fantastic for cellular level organelles but it doesn't quite get down to the same resolution something lik…
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Comment #47634356
Honestly, this is a good thing. OpenClaw as a concept was rather silly to run such a heavy model for. If you want something like OpenClaw to work you really need to figure out how …
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Comment #47634235
Honestly, it'd be really funny to try and make a CLAUDE.md file for slop maxxing.
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Comment #47618668
I'm not convinced people who are doing real work on production applications with any sizable user base is writing code through only agents. There's no way to get acceptable code fr…
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Comment #47618611
Oh my god, this comment gave me flashbacks to when I was writing android apps in Eclipse + ADT
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Comment #47618517
> We very much still believe this That's good to hear, I might have jumped a little too quickly in my opinion. It's a bit of a Pavlovian response at this point seeing a product I v…
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Comment #47618440
Yeah that's the disconnect though right? Even with the best frontier models, you need to do a lot of system design work, planning, and reviewing before you can let these models run…
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Comment #47618253
Man, I wish they'd keep the old philosophy of letting the developer drive and the agent assist. I feel like this design direction is leaning more towards a chat interface as a firs…
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Comment #47614323
I wonder how much of this is also used for audience segmentation for their advertisements? Linkedin ads are some of the most expensive out of any social media platform, but they al…
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Comment #47591965
>But if your workload is not shifting from write-heavy to read-heavy, you inevitably will be responsible for a major outage or quality issue. I think that's actually a good way to …
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Comment #47591456
>slop cannons I am stealing that phrase haha
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Comment #47591437
Yeah, I'm not trying to defend slop. I don't think all means-to-end people are just in it for money, I'll use the anecdote of myself. My team is working on a CAD for drug discovery…
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Comment #47591342
The public doesn't care about the code itself, they absolutely care about the quality and experience of using the software. But you can have an extremely well designed product that…