Viewing profile — refurb

While the debt numbers might look large, don't forget how much revenue is coming into these companies as well. OpenAI gross revenue was $4B in 2024, $13B in 2025 and estimated to h…

I would question the idea that highly industry consolidated debt is competing with risk free debt issued by the US government. Those are two very different products. And while the …

By that measure it doesn’t sound like that much. You’re talking about about an amount that is a 13% of the total US government spending, of which is 20% of the entire US GDP. I’m n…

It sounds like you can’t grasp a discussion on another topic yet you insert yourself into it.

It seems like your desperation to make a point has caused you to goal pole shift a second time!

DMF is quite different than acetone. As a chemist it’s a highly polar, very high boiling point solvent that is the “go to” when you can’t find a solvent your reactants dissolve in.…

As someone who immigrated to the US and has been detained in secondary inspection I can assure you I do have knowledge in this area.

I mean the guy didn’t have proper documentation and admitted to illegally entering the US (not at a crossing I assume). It’s a completely different situation.

Maybe, but being detained for a couple hours is better than committing a felony, no?

CBP doesn't need a warrant to search at the border, including electronic devices. However, if Tunick was smart he would have refused to provide the PIN, and let them seize it. He'l…

A far better approach is for the US citizen to simply say "I chose not to provide my PIN". The officer will say something like "That's your choice, but I will need to seize the dev…

> It's people who couldn't get out of jury duty. But that's good no? People who got out never would have taken it seriously. I sat on a jury trial and was highly impressed with how…

>U.S. law though is highly non-autistic LOL, that made me chuckle. People somehow think they're the first one to think of a workaround to a law, when in fact it's been happening si…

Lots of examples of older drugs currently in use that are potent hERG inhibitors: haloperidol (antipsychotic), ketoconazole (antifungal), erythromycin (antibiotic), domperidone (an…

Look at the GLP-1s. Lilly spent tens hundreds of millions developing an oral version that was otherwise the same as the injectable’s. And the notorious inhaled insulin that Pfizer …

It’s a similar problem you see with all safety related decisions - as the large risks are eliminated you become more concerned about the smaller risks. Plenty of successful drugs f…

> Failed attempts cost society nearly nothing The world does not have unlimited resources. Money spent on one project is money that can’t be spent on another.

As someone who used to work in pharmaceutical R&D, the important thing to remember is the hurdle to get over hasn’t remained constant. The FDA has gotten significantly more strict …

Zolgensma acts on the peripheral motor neurons not the CNS

The US title system varies by state. Some are deeds based others are Torrens (registry), though deeds based dominates. And as for being screwed, that’s why real estate transactions…

Clarifying definition is not a "word game". You seem quite uncomfortable debating the facts, and that's ok.

Hmmm, this index scores US at 80% and Mexico at 86%. To say the results are suspect is understating things.

I never said no one would be bankrupted by ambulance fees. We’re talking about financial ruin of the government.

Your article is about landlines AND they received government approval to end service. We’re talking about remote areas of the US that have almost no local population. Why would a c…

That seems like an impossible task in today’s world of layoffs and needing to jump jobs to get pay raises. You could live where you work and suddenly your next job is a 30 min driv…