Viewing profile — ramanujan

You are insane. No charity will accept an amount of 500 uBTC. They're probably batching the donations and then sending them in bulk.

Very interesting and highly creative. A few thoughts. 1) If a graphical plot turns data into something visual, an audio "plot" turns data into something audible. Your output is an …

I believe the rule of thumb is that there are 15 that reach $100M revenue . We could square the figure of 200 at $100M valuation with this rule of thumb if we assume valuation is s…

This is amazing work. Could you explain why you decided to go with many individual stills rather than filling in the gaps in a video codec? It's a really counterintuitive approach.…

Genomics is now in the clinic in a big way, albeit for diagnostics rather than cures. Two recent links you might find informative: http://techcrunch.com/2013/04/23/counsyl http://t…

Datastax, Datastax. Must have appeared 20 times in the piece. I'm sure they are a great company but Oracle's real problem is Postgres (and, to a lesser extent, SQLite and the vario…

Can you put an email in your profile? We've got some people independently interested in the Bitcoin-for-Cyprus thing.

It looks like this possibility was known and broadcasted to merchants during the maintenance window two days ago. It's kind of like the Rails mass assignment or security bug: merch…

Strongly agree. If he names names, something good might come of this now that it has HN's attention for the day. And if he was going to journalists, he had a willingness to name na…

People can inject just about anything they want into themselves Actually, that is expressly not what the Cowan or the earlier Rutherford decision on Laetrile say. http://www.leagle…

Three points. First, many (most?) medical advances seem crazy and kooky because they haven't been tried before. So it's not usually as obvious as "this is a proven scam" vs. "this …

You might be interested in these studies. The second link is to a discussion of Andy Grove's editorial in Science calling for the FDA to only certify safety (rather than safety + e…

The issue is not really whether these treatments work or not. Every new treatment is by necessity unproven and more risky than an established one. Some people are early adopters or…

I remember reading an academic article that showed how the real cost was almost always 1/20 of that This is the Light and Warburton study. The short answer is that it's kind of lik…

First off, I am happy that we both seem to agree on a qualitative fact: there is indeed a tradeoff between what statisticians call type I and type II errors. At one extreme, you ca…

So, regarding efficacy testing, I think the costs/benefits have to be assessed in full context. If you go back to the time before the FDA, it was a time of incredible wonder drugs …

So, a few points (I didn't downvote you). 1) First, FDA fast-tracks many bad things. Hundreds of millions of people were irradiated by scanners that FDA waved on through because a …

Lot of important points to engage there, and generally agree with the spirit of the comments. I think many biotech startups would instantly take a deal that gave them and their pat…

approved treatments in humans often lag 10 years or so behind what's known to work in animal models The reason for this is regulation and IRB. I direct you to Banting and Best (whi…

Let's go point by point. 1) Regarding diabetes and the FDA: I don't think removing the FDA is going to find a cure for diabetes. Well, before the FDA as such even existed, Banting …

Right, but if there were a private system similar to the one in which Underwriters Laboratories operates, that'd be preferable. I'm not sure how to get there from here, which is wh…

Good question. Broadly speaking, the whole regulatory space (not just FDA, but all other agencies) is indeed a massive business opportunity. There are basically two ways to operate…

2. There are regulatory obstacles for businesses. As someone in the biotech space, this is by far the biggest factor. When you are dealing with humans, crashes and bugs mean deaths…