Viewing profile — ptest1

Not only that, but many nonprofits must force their employees and even volunteers to use annoying time tracking software!

I was floored to discover Reddit is violating Google’s Auth TOS! Check this out: 1. Log in using your Google account. 2. Log out of reddit. 3. Clear your Reddit cookies. 4. Visit R…

In large dense American cities there are risks with even going outside on a walk. There are stories of people who didn’t leave their homes except on walks but caught COVID-19. Ther…

I added “beside the point” because I believe so, yeah.

None of the items were life or death essentials. These were things like protein cookies, pet-themed gifts, exercise equipment, etc. I wouldn’t have bought them if I never saw the a…

I might be one of the few, but I like the ads I see on Instagram and have purchased lots of things via IG ads. I can’t think of any other app/site where the ads have sucked me in. …

The problem I see with this trial is that it’s open-label, small n, and has subjective endpoints (ICU admission as the primary outcome). The study is underpowered to detect mortali…

I guess what I think could be possible is: ARBs upregulate ACE2 but within normal physiological limit (see other comment). My understanding is it is the Ang II activation of AT2R t…

Just a little clarification. These renin-angiotensin terms are totally confusing (due to how similar they all are!) and from my correspondence with physicians, many of them even ge…

As far as I can tell, there are no studies showing a higher ACE2 causes more severe disease. Sure, it could, but the pathophysiological models and animal data suggest that it is th…

I wrote a long comment and it got deleted, argh! Best guess? ACE2 loss is probably bad, having more ACE2 probably doesn’t drive disease severity: https://twitter.com/__philipn__/st…

They won’t block ACE2 but as indicated in the article they may prevent the lung damage associated with SARS by blocking AT1R which is the receptor that may mediate lung damage. The…

This wasn’t in a petri dish actually, this was an in vivo study using mice. Other in vivo studies show similar. There are actually no known trials with ARBs and SARS-CoV-2, which i…

Excessive unrelated business income causes a loss of public charity status due to failing the public support test. In this case it’s moot because ISOC is giving up on their status …

(I also work in the nonprofit space) In this case, ISOC should almost certainly lose their 501(c)3 status, as the transaction is unrelated business income, and may or may not have …

The mass complaints work very well when backed by an organized effort to lobby, press attention, etc. There are people vulnerable to political and social pressure who make decision…

The former CEO of ICANN basically started the PE firm PIR was “sold” to: https://www.privateinternetaccess.com/blog/2019/11/isoc-pir-... ICANN, by lifting the price restriction, wa…

I’m doing this! Both for PIR and ICANN. Please see my other comment on this thread. It is likely this “sale” could be considered illegal. Here is the information for ICANN which ca…

I don’t understand how this “sale” is legal in the first place. PIR is a legal 501(c)3 nonprofit. You can’t really sell a nonprofit to a for-profit company except in unusual and ra…