Live data from Hacker News

Viewing profile — paulfharrison

paulfharrison

HN member
Joined
Sun, Nov 07, 2021, 9:07 PM UTC
HN karma
21
Public activity
19 items

About paulfharrison

I am a bioinformatician with the Genomics and Bioinformatics Platform at Monash University.

Recent public activity

  1. comment
    Comment #49176557

    A comment by Norbert Wiener on translation machines (published 1993 but written somewhat earlier in "Invention: The Care and Feeding of Ideas"): "Thus the effect of the machine of …

  2. comment
    Comment #48378779

    It's nice to see sparse interpretable LLMs being made. This is similar to factor rotation in factor analysis (or PCA). A varimax rotation, for example, can produce an equivalent fa…

  3. comment
    Comment #47905470

    This advice can also be applied to PhD thesis examinations and paper reviews.

  4. comment
    Comment #47774326

    My dad is in his 80s. He keeps careful notes on how to use devices like tablets and TVs. There might be a touch of engineer-brain at work here, but the struggle is very real. He ge…

  5. comment
    Comment #46495050

    For linear models, least squares leads to the BLUE estimator: Best Linear Unbiassed Estimator. This acronym is doing a lot of work with each of the words having a specific technica…

  6. comment
    Comment #46493459

    A note mostly about terminology: The least squares model will produce unbiassed predictions of y given x, i.e. predictions for which the average error is zero. This is the usual te…

  7. comment
    Comment #46159446

    535.491…^i = 1

  8. comment
    Comment #46048943

    R is so good in part because of the efforts of people like Di Cook, Hadley Wickham, and Yihui Xie to create an software environment that they like working in. It also helps that in…

  9. comment
    Comment #45638960

    Producing a diverse list of results may still help in a couple of ways here. * If there are a lot of lexical matches, real semantic matches may still be in the list but far down th…

  10. comment
    Comment #44373046

    Here's a scenario. You're running a cluster, and your users are biologists producing large datasets. They need to run some very specific command line software to assemble genomes. …

  11. comment
    Comment #44326165

    What a strange web page. Scrolling is thoroughly broken. I recently went to a two day workshop on whole cell modelling. I'm still trying to work out how much of the exercise is fan…

  12. comment
    Comment #43178285

    Thanks for this. Despite the vintage this seems very clearly written, the introductory material on measure theory has already made it worthwhile for me.

  13. comment
    Comment #43168005

    As others have said in various ways, start by fitting a survival model using glmnet. That said, here are some folks trying to use SDEs to model cells, they even have a "dW" on thei…

  14. comment
    Comment #43164987

    A further step is Langevin Dynamics, where the system has damped momentum, and the noise is inserted into the momentum. This can be used in molecular dynamics simulations, and it c…

  15. comment
    Comment #42953761

    It could also be that the aspect of personality that causes people to think Kagi is better also causes those people to buy it.

  16. comment
    Comment #42811546

    Brownian motion mentioned at the end of the article and more generally Langevin Dynamics are incredibly useful. They're this weird interface between normal physics and statistical …

  17. comment
    Comment #42448721

    If you plot x^y against x+y, you get a Sierpinski triangle.

  18. comment
    Comment #41795847

    The article mentions equivalent ranking from cosine similarity and Euclidean distance. The derivation is very simple. For vectors A and B, the squared Euclidean distance is: (A-B).…

  19. comment
    Comment #41684043

    For web-servers on remote machines, I have found this useful: socat TCP4-LISTEN:1234,fork,bind=127.0.0.1 EXEC:'ssh my.remote.server nc 127.0.0.1 1234' 1234 = local/remote port. Can…