Viewing profile — panabee
panabee
HN member- Joined
- Mon, Jul 04, 2011, 9:00 AM UTC
- HN karma
- 4,353
- Public activity
- 1,028 items
- HN profile
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About panabee
X.com/panabee
Please message for free Hotpot credits. HN is an invaluable source of knowledge. I would be honored to give back.
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Papers:
Hotpot-JOMI: Joint Outcome Model Interrogation for Reasoning Consistency
Patient.md: Framework to Organize Medical Data for AI Assistants
M.I.J.O.: Framework for Evaluating Applicability and Limitations of Biomedical Datasets with AI Assistants
Infection-Associated ME/CFS: Phenotypic Overlap, Craniofacial-to-Intracranial Sampling, and the J.O.A.N.-M.I.K.E. Frameworks
Reevaluating the Association Between Epstein-Barr Virus (EBV) and Breast Cancer in the United States
Recent public activity
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Comment #49238409
The overall dataset was very large (8,972,221 deaths), but only 1,348 ambulance drivers were included, and just 10 had Alzheimer’s disease as the underlying cause of death. Such a …
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Comment #48016203
How to notify you once v0 is ready -- just comment here?
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Comment #48016197
How to notify you once v0 is ready -- just comment here?
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Comment #48004417
Will aim to ground the framework -- Cancer Mini-101 for Engineers -- in personal use cases. I hope it will be helpful for you.
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Comment #48004395
Great question. The bar for proof in biomedicine is naturally high. I only shared facts because so much is unknown. If you can find a lab exploring the question, maybe you can supp…
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Comment #48004375
I will aim to put together a Cancer 101 for engineers, not sure how to share. Maybe I'll post here or will post to our biomedical GitHub so it can evolve over time?
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Comment #48003316
For people questioning why to involve GPT and AI assistants: GPT and AI assistants cannot be fully trusted, but they can personalize learning. The chief challenge for the framework…
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Comment #48000546
On second thought, I will publish something regardless of interest. It will be an "Cancer for Engineers" framework, delivered via free, open-source Custom GPTs and Claude Skills. (…
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Comment #47999670
Here are more fascinating facts about caffeine and cancer. Caffeine affects the immune system via at least two opposing mechanisms. Mechanism 1: A2A receptor antagonism (immunostim…
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Comment #47906580
If you're a wealthy person lacking a neurobiology background, how do you decide which research efforts are the most promising? Which labs do you back? Generally, you rely on expert…
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Comment #47906440
TLDR: gatekeepers stifled exploration and innovation. When a topic only has a limited number of experts, those experts become gatekeepers. Those gatekeepers directly or indirectly …
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Comment #47834497
VCs are soccer stars, but founders play basketball. It’s easy to dunk on VCs, but the herd effect is rational after considering the typical VC’s background, the intense competition…
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Comment #45391432
The association between pathogens and cancer is under-appreciated, mostly due to limitations in detection methods. For instance, it is not uncommon for cancer studies to design ass…
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Comment #45349553
A more accurate title: "Are Cornell Students Meritocratic and Efficiency-Seeking? Evidence from 271 MBA students and 67 Undergraduate Business Students." This topic is important an…
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Comment #44661729
Thanks. This is helpful. Looking forward to more of your thoughts. Some nuance: What happens when the methods are outdated/biased? We highlight a potential case in breast cancer in…
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Comment #44659912
Valid critique, but one addressing a problem above the ML layer at the human layer. :) That said, your comment has an implication: in which fields can we trust data if incentives a…
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Comment #44659460
If you agree that ML starts with philosophy, not statistics, this is but one example highlighting how biomedicine helps model development, LLMs included. Every fact is born an opin…
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Comment #44657381
100% agreed. I also advise you not to read many cancer papers, particularly ones investigating viruses and cancer. You would be horrified. (To clarify: this is not the fault of sci…
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Comment #44657337
To elaborate, errors go beyond data and reach into model design. Two simple examples: 1. Nucleotides are a form of tokenization and encode bias. They're not as raw as people assume…
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Comment #44657056
This is long overdue for biomedicine. Even Google DeepMind's relabeled MedQA dataset, created for MedGemini in 2024, has flaws. Many healthcare datasets/benchmarks contain dirty da…
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Comment #44652872
The author is a respected voice in tech and a good proxy of investor mindset, but the LLM claims are wrong. They are not only unsupported by recent research trends and general patt…
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Comment #44539041
More like alarming anecdote. :) Google did a wonderful job relabeling MedQA, a core benchmark, but even they missed some (e.g., question 448 in the test set remains wrong according…
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Comment #44526043
Thanks, but no one truly understands biomedicine, let alone biomedical ML. Feynman's quote -- "A scientist is never certain" -- is apt for biomedical ML. Context: imagine the human…
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Comment #44516197
Agreed. There is deep potential for ML in healthcare. We need more contributors advancing research in this space. One opportunity as people look around: many priors merit reconside…